Results 41 to 50 of about 393,599 (169)

Lymphangiogenesis and breast cancer metastasis.

Histology and histopathology, 2002
Breast cancer is one of the commonest malignancies in women in the western world. It spreads predominantly via the lymphatic system. However, the understanding of the formation of lymphatics, lymphangiogenesis, has been limited. This has been largely due to the previous lack of lymphatic specific markers.
Cunnick, G.H., Jiang, W.G., Gomez, K.F., Mansel, R.E.   +3 more
openaire   +3 more sources

The Role of Autophagy in Breast Cancer Metastasis

Biomedicines, 2023
Patient morbidity and mortality is significantly increased in metastatic breast cancer. The metastasis process of breast cancer is very complicated and is delicately controlled by various factors.
Hye Min Kim, Ja Seung Koo
doaj   +1 more source

In vivo validation of metastasis-regulating microRNA-766 in human triple-negative breast cancer cells

Laboratory Animal Research, 2017
Breast cancer is the second most common cancer and the most frequent cancer in women worldwide. Recent improvements in early detection and effective adjuvant chemotherapies have improved the survival of breast cancer patients.
Keunhee Oh, Dong-Sup Lee
doaj   +1 more source

C3a-C3aR signaling promotes breast cancer lung metastasis via modulating carcinoma associated fibroblasts

Journal of Experimental & Clinical Cancer Research, 2020
Background Mounting evidence suggests that complement components promote tumor progression via modulating immune suppression, angiogenesis, or tumor cell proliferation.
Chi Shu, Haoran Zha, Haixia Long, Xinxin Wang, Fei Yang, Jianbao Gao, Chunyan Hu, Li Zhou, Bo Guo, Bo Zhu   +9 more
doaj   +1 more source

Emodin attenuates high lipid-induced liver metastasis through the AKT and ERK pathways in vitro in breast cancer cells and in a mouse xenograft model

Heliyon, 2023
Emodin, a natural anthraquinone derivative, can inhibit lipid synthesis and breast cancer cell proliferation. We previously found that emodin decreased breast cancer liver metastasis via epithelial-to-mesenchymal transition (EMT) inhibition. However, the
Feng Li, Xiaoyun Song, Xiqiu Zhou, Lili Chen, Jinzhou Zheng   +4 more
doaj   +1 more source

A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images

Communications Medicine
Background The objective of this comprehensive pan-cancer study is to evaluate the potential of deep learning (DL) for molecular profiling of multi-omic biomarkers directly from hematoxylin and eosin (H&E)-stained whole slide images.
Salim Arslan, Julian Schmidt, Cher Bass, Debapriya Mehrotra, Andre Geraldes, Shikha Singhal, Julius Hense, Xiusi Li, Pandu Raharja-Liu, Oscar Maiques, Jakob Nikolas Kather, Pahini Pandya   +11 more
doaj   +1 more source

Orbital Metastasis of Breast Carcinoma

Breast Cancer: Basic and Clinical Research, 2009
We report a case of orbital metastasis in a previously diagnosed metastatic breast cancer in a 46-year old woman presenting with diplopia and proptosis of her left eye bulb. An orbital computed-tomography (CT) and a magnetic resonance imaging (MRI) both revealed an intra-orbital extra-bulbar mass of 1.5 × 3 cm in size, in the left orbit.
Panagiotis J, Vlachostergios, Ioannis A, Voutsadakis, Christos N, Papandreou   +2 more
openaire   +2 more sources

Heterogeneous nuclear ribonucleoprotein A2/B1 is a negative regulator of human breast cancer metastasis by maintaining the balance of multiple genes and pathways

EBioMedicine, 2020
Background: Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is an important RNA-binding protein that affects the RNA processing, splicing, transport and stability of many genes. hnRNPA2/B1 is expressed during proliferation and metastasis of various
Yu Liu, Huan Li, Fan Liu, Li-Bin Gao, Rong Han, Chen Chen, Xue Ding, Shuang Li, Kun Lu, Ling Yang, Hui-Min Tian, Bin-Bin Chen, Xiao Li, Dong-Hui Xu, Xiao-Ling Deng, Song-Lin Shi   +15 more
doaj   +1 more source

Construction and validation of a 6-gene nomogram discriminating lung metastasis risk of breast cancer patients.

PLoS ONE, 2020
Breast cancer is the most common malignant disease in women. Metastasis is the foremost cause of death. Breast tumor cells have a proclivity to metastasize to specific organs.
Lingchen Wang, Wenhua Wang, Shaopeng Zeng, Huilie Zheng, Quqin Lu   +4 more
doaj   +1 more source

Nuclear import of PTPN18 inhibits breast cancer metastasis mediated by MVP and importin β2

Cell Death and Disease, 2022
Distant metastasis is the primary cause of breast cancer-associated death. The existing information, such as the precise molecular mechanisms and effective therapeutic strategies targeting metastasis, is insufficient to combat breast cancer.
Tao Wang, Xinlei Ba, Xiaonan Zhang, Na Zhang, Guowen Wang, Bin Bai, Tong Li, Jiahui Zhao, Yanjiao Zhao, Yang Yu, Bing Wang   +10 more
doaj   +1 more source