Results 101 to 110 of about 1,935,876 (396)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Cytokines and Soluble Receptors in Breast Milk as Enhancers of Oral Tolerance Development

Frontiers in Immunology, 2019
The postpartum period is an important window during which environmental factors can shape the life-long health of the infant. This time period often coincides with substantial milk consumption either in the form of breast milk or from cow's milk sources,
Bassel Dawod, J. Marshall
semanticscholar   +1 more source

Comparative Study on Lipid Dynamics in Maternal Breast Milk between Preterm and Term Infants of Han Ethnicity in Northwestern China [PDF]

Shipin Kexue
Objective: To conduct comparative analysis of the dynamic trend of breast milk lipid composition across different lactation stages in mothers of preterm and term infants with the aim of providing a basis for optimizing feeding strategies for preterm ...
FENG Yan, WANG Xinyue, XUE Jianlan, LUO Xiaoqin, SU Li, LI Ting, DUAN Sufang, LIU Biao, SITU Wenyou
doaj   +1 more source

Perbedaan Pemberian Asi Ekslusif Dan Asi Non Ekslusif Dengan Perubahan Berat Badan Pada Bayi Di Puskesmas Bahu Manado [PDF]

, 2016
:Exclusive breast milk is the milk given to babies from birth without be given other foods until the baby is 6 months old .A milk formula can be given to infants 0-6 months , but only given if milk production is not sufficient for the baby .
Hamel, R. (Rivelino), Lutur, J. K. (Jane), Rottie, J. (Julia)   +2 more
core  

“Exosomics”—A Review of Biophysics, Biology and Biochemistry of Exosomes With a Focus on Human Breast Milk

Frontiers in Genetics, 2018
Exosomes are biomolecular nanostructures released from cells. They carry specific biomolecular information and are mainly researched for their exquisite properties as a biomarker source and delivery system.
Carolina de la Torre Gómez, Renee V. Goreham, J. J. Bech Serra, T. Nann, M. Kussmann   +4 more
semanticscholar   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

Impact of Maternal Nutrient Consumption on Human Milk Macro Nutrient Composition: A Cross-Sectional Study

Çocuk Dergisi
Objective: To increase the production of human milk, mothers must have an adequate, balanced, and healthy diet. This study investigated the effect of maternal food consumption on the macronutrient composition of breast milk. Methods: This cross-sectional
Fatma Şule Bilgiç, Gülçin Bozkurt, Emine Asuman Çoban   +2 more
doaj   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

IMMUNOGENIC FACTORS OF THE BREAST MILK DURING ITS PROLONGED STORAGE UNDER LOW TEMPERATURES

Вопросы современной педиатрии, 2013
The data on the influence of the prolonged low temperatures effect (-20°C) on the immunogenic factors of the breast milk is shown in the article. The received during the study new data on the stability of the secretory immunoglobulin A in the breast milk
E. I. Kondrat'eva, D. E. Khapacheva, A. I. Tlif, L. A. Podporina, S. V. Storozhuk   +4 more
doaj   +1 more source