Results 161 to 170 of about 1,935,876 (396)

Prolonged Neonatal Unconjugated Hyperbilirubinemia Associated with Breast Feeding and a Steroid, Pregnane-3 (Alpha), 20 (Beta)-Diol, in Maternal Milk That Inhibits Glucuronide Formation In Vitro* [PDF]

, 1964
Irwin M. Arias, Lawrence M. Gartner, Sam Seifter, Mathilda Furman   +3 more
openalex   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

Cimetidine excretion into breast milk. [PDF]

, 1979
Andrew A. Somogyi, R Gugler
openalex   +1 more source

Tumor Extracellular Vesicles Aggravate Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
This study reveals a novel mechanistic connection between cancer and ischemia/reperfusion (I/R)‐induced cardiac injury. The meta‐analysis demonstrates significantly higher incidence ratios of both all‐cause mortality and cardiovascular mortality in cancer patients undergoing percutaneous coronary intervention (PCI) compared to non‐cancer patients.
Zhongting Mei, Qian Liu, Guoxin Liu, Manjie Zhang, Jiaxin Fang, Xuting He, Xueqi He, Zhengwei Qin, Ronghua Liu, Chuang Liu, Hongyu Ji, Yuechao Dong, Ye Yuan, Baofeng Yang, Weijie Du   +14 more
wiley   +1 more source

Antimicrobial protein and Peptide concentrations and activity in human breast milk consumed by preterm infants at risk of late-onset neonatal sepsis.

PLoS ONE, 2015
ObjectiveWe investigated the levels and antimicrobial activity of antimicrobial proteins and peptides (AMPs) in breast milk consumed by preterm infants, and whether deficiencies of these factors were associated with late-onset neonatal sepsis (LOS), a ...
Stephanie Trend, Tobias Strunk, Julie Hibbert, Chooi Heen Kok, Guicheng Zhang, Dorota A Doherty, Peter Richmond, David Burgner, Karen Simmer, Donald J Davidson, Andrew J Currie   +10 more
doaj   +1 more source

BREAST-MILK MONITORING TO MEASURE MICHIGAN'S CONTAMINATION WITH POLYBROMINATED BIPHENYLS [PDF]

, 1978
Lawrence B. Brilliant, George Van Amburg, John L. Isbister, Harold E. B. Humphrey, Kenneth R. Wilcox, Janet Eyster, Arthur W. Bloomer, Harold A. Price   +7 more
openalex   +1 more source

Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil [PDF]

, 2003
Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Cole, T.J., Treleaven, P., Wells, J.C.K.
core  

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Day/night fluctuations of breast milk bioactive factors and microbiome

Frontiers in Nutrition
IntroductionHuman breast milk is a sophisticated and complex biological fluid that provides crucial nutritional, immunological, and microbial benefits to infants.
Melissa A. Woortman, Haipeng Sun, Jincheng Wang, Filipa Godoy-Vitorino, Angeliz J. Rivera Meléndez, Maribel Campos Rivera, Edna E. Aquino Piñero, Krystin Engelhardt, Lawrence C. Kleinman, Lawrence C. Kleinman, Lawrence C. Kleinman, Maria G. Dominguez-Bello, Maria G. Dominguez-Bello, Maria G. Dominguez-Bello   +13 more
doaj   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source