This study identifies a novel mechanism of nasopharyngeal carcinoma (NPC) cisplatin chemoresistance that DDAH1 expression is associated with cisplatin resistance in NPC cells primarily through the enhancement of the phosphoinositide Janus kinase 2 (JAK2)‐signal transducer and activator of transcription 3 (STAT3) pathway.
Jin‐Hao Yang+10 more
wiley +1 more source
Identification of nanoparticle infiltration in human breast milk: Chemical profiles and trajectory pathways. [PDF]
Yang Q+6 more
europepmc +1 more source
Concentrations of lead in maternal blood, cord blood, and breast milk. [PDF]
Choon Nam Ong+4 more
openalex +1 more source
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu+7 more
wiley +1 more source
Nutrition With Skimmed Breast Milk in an Infant With Long Chain 3-Hydroxyacyl-coA Dehydrogenase Deficiency. [PDF]
Alonso-Diaz C+7 more
europepmc +1 more source
Energy balance, nitrogen balance, and growth in preterm infants fed expressed breast milk, a premature infant formula, and two low-solute adapted formulae. [PDF]
O G Brooke, Carole Wood, Jackie Barley
openalex +1 more source
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong+11 more
wiley +1 more source
The Impact of Substance Use Disorder and Drug Transfer into Breast Milk: Implications for Maternal and Infant Health. [PDF]
Yang Y, Yi B, Zhang T.
europepmc +1 more source