Results 71 to 80 of about 1,744,838 (315)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Impact of Maternal Nutrient Consumption on Human Milk Macro Nutrient Composition: A Cross-Sectional Study

open access: yesÇocuk Dergisi
Objective: To increase the production of human milk, mothers must have an adequate, balanced, and healthy diet. This study investigated the effect of maternal food consumption on the macronutrient composition of breast milk. Methods: This cross-sectional
Fatma Şule Bilgiç   +2 more
doaj   +1 more source

Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages.

open access: yesJournal of Clinical Investigation, 2019
Prevalence of obesity among infants and children below 5 years of age is rising dramatically, and early childhood obesity is a forerunner of obesity and obesity-associated diseases in adulthood.
Haidong Yu   +20 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Comparative Study on Lipid Dynamics in Maternal Breast Milk between Preterm and Term Infants of Han Ethnicity in Northwestern China [PDF]

open access: yesShipin Kexue
Objective: To conduct comparative analysis of the dynamic trend of breast milk lipid composition across different lactation stages in mothers of preterm and term infants with the aim of providing a basis for optimizing feeding strategies for preterm ...
FENG Yan, WANG Xinyue, XUE Jianlan, LUO Xiaoqin, SU Li, LI Ting, DUAN Sufang, LIU Biao, SITU Wenyou
doaj   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Short-chain fatty acids in breast milk and their relationship with the infant gut microbiota

open access: yesFrontiers in Microbiology
IntroductionThe short-chain fatty acids (SCFAs) contained in breast milk play a key role in infant growth, affecting metabolism and enhancing intestinal immunity by regulating inflammation.MethodsIn order to examine the associations between the ...
Menglu Xi   +10 more
doaj   +1 more source

Micronutrient intakes of lactating mothers and their association with breast milk concentrations and micronutrient adequacy of exclusively breastfed Indonesian infants

open access: yesAmerican Journal of Clinical Nutrition, 2019
Background Breast milk is the sole source of nutrition for exclusively breastfed infants in the first 6 mo of life, yet few studies have measured micronutrient concentrations in breast milk in light of maternal diet and subsequent infant micronutrient ...
L. Daniels   +12 more
semanticscholar   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

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