Results 41 to 50 of about 138,513 (347)
The Thorium Molten Salt Reactor : Moving on from the MSBR [PDF]
, 2005 A re-evaluation of the Molten Salt Breeder Reactor concept has revealed problems related to its safety and to the complexity of the reprocessing considered.
A. Nuttin +14 more
core +3 more sources
Energies, 2021 Magnetohydrodynamic (MHD) phenomena, due to the interaction between a magnetic field and a moving electro-conductive fluid, are crucial for the design of magnetic-confinement fusion reactors and, specifically, for the design of the breeding blanket ...
Lorenzo Melchiorri +4 more
doaj +1 more source
A Thermal Discrete Element Analysis of EU Solid Breeder Blanket subjected to Neutron Irradiation
, 2014 Due to neutron irradiation, solid breeder blankets are subjected to complex thermo-mechanical conditions. Within one breeder unit, the ceramic breeder bed is composed of spherical-shaped lithium orthosilicate pebbles, and as a type of granular material ...
Annabattula, Ratna +5 more
core +1 more source
Nuclear Fusion, 2023 In most scenarios, the vertical displacement event (VDE) represents the most extreme electromagnetic (EM) event within the tokamak device. The significant EM loads experienced during this event have the potential to compromise the structural stability of
Mingzhun Lei +4 more
doaj +1 more source
New simulations to qualify eutectic lithium-lead as breeder material [PDF]
, 2011 Pb17Li is today a reference breeder material in diverse fusion R&D programs worldwide. One of the main issues is the problem of liquid metals breeder blanket behavior.
Caro, Alfredo +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Nuclear Analysis, 2023 In order to have a deep understanding of the tritium migration and release mechanisms in ceramic breeders, computer simulation of the tritium release behavior of Li4SiO4 ceramic breeder was performed by using an improved tritium release model.
Guangming Ran +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source