Results 51 to 60 of about 9,751 (308)

Study on Multiphysics Coupling and Automatic Neutronic Optimization for Solid Tritium Breeding Blanket of Fusion Reactor

Energies, 2021
A tritium breeding blanket (TBB) is an essential component in a fusion reactor, which has functions of tritium breeding, energy generation and neutron shielding.
Shen Qu, Qixiang Cao, Xuru Duan, Xueren Wang, Xiaoyu Wang   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

IFE Plant Technology Overview and contribution to HiPER proposal

, 2011
HiPER is the European Project for Laser Fusion that has been able to join 26 institutions and signed under formal government agreement by 6 countries inside the ESFRI Program of the European Union (EU). The project is already extended by EU for two years
Alvarez Ruiz, Jesus, Cereceda, D., Courtin, Sergio, Cuesta Lopez, Santiago, Fernández, J., Fraile García, Alberto, Garoz Gómez, David, Gonzalez Arrabal, Raquel, Gordillo, N., Guerrero, Carlo, Juarez Mañas, Rafael, Moral Fernández, Nuria, Ognissanto, Flora, Perlado Martín, José Manuel, Rio Redondo, Emma del, Rivera de Mena, Antonio, Sanz, J., Suarez, R., Sánchez, C., Victoria, M.   +19 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Study on the flow and heat transfer characteristics of Li4SiO4 pebble bed based on DEM-CFD coupling

International Journal of Advanced Nuclear Reactor Design and Technology
The blanket is a key component for producing tritium in fusion reactors. To ensure the blanket operates effectively and safely, it is crucial to maintain efficient heat transfer in the pebble bed. Furthermore, the breeder material needs to operate within
Fangrui Guo, Qiang Lian, Shanshan Bu, Liangming Pan   +3 more
doaj   +1 more source

Development of a three-dimensional method for thermal-hydraulics/neutronics coupling analysis and its application on CFETR helium-cooled solid breeder blanket

International Journal of Advanced Nuclear Reactor Design and Technology, 2021
Blankets are of practical importance in the fusion reactor due to their main functions for engineering application. As the fusion power designed for the Chinese Fusion Engineering Test Reactor (CFETR) is increased from 200 MW to 1.5 GW during its phase ...
Qiang Lian, Wenxi Tian, Suizheng Qiu, G.H. Su   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Liquid lead and Lithium. A Comprehensive molecular dynamics study [PDF]

, 2011
Pb17Li is today a reference breeder material in diverse fusion R&D programs worldwide. One of the main issues in these programs is the problem of liquid metals breeder blanket behavior.
Caro, Alfredo, Cuesta Lopez, Santiago, Fraile García, Alberto, Perlado Martín, José Manuel   +3 more
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source