Results 41 to 50 of about 9,751 (308)
In most scenarios, the vertical displacement event (VDE) represents the most extreme electromagnetic (EM) event within the tokamak device. The significant EM loads experienced during this event have the potential to compromise the structural stability of
Mingzhun Lei +4 more
doaj +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
In order to have a deep understanding of the tritium migration and release mechanisms in ceramic breeders, computer simulation of the tritium release behavior of Li4SiO4 ceramic breeder was performed by using an improved tritium release model.
Guangming Ran +3 more
doaj +1 more source
Numerical study of laminar magneto-convection in a differentially heated square duct [PDF]
Magnetohydrodynamic pressure drops are one of the main issues for liquid metal blanket in fusion reactors. Minimize the fluid velocity at few millimeters per second is one strategy that can be employed to address the problem.
Caruso, Gianfranco +2 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Main Nuclear Responses of the DEMO Tokamak with Different In-Vessel Component Configurations
Research and development of the DEMOnstration power plant (DEMO) breeder blanket (BB) has been performed in recent years based on a predefined DEMO tritium breeding ratio (TBR) requirement, which determines a loss of wall surface due to non-breeding in ...
Jin Hun Park, Pavel Pereslavtsev
doaj +1 more source
Methodology for accident analyses of fusion breeder blankets [PDF]
‘Fusion for Energy’ (F4E) is designing, developing, and implementing the European Helium-Cooled Lead-Lithium (HCLL) and Helium-Cooled Pebble-Bed (HCPB) Test Blanket Systems (TBSs) for ITER (Nuclear Facility INB-174). Safety demonstration is an essential element for the integration of these TBSs into ITER and accident analysis is one of its critical ...
Dobromir Panayotov +12 more
openaire +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Long-term corrosion behavior of ODS-Eurofer in flowing Pb-15.7Li at 550°C
Low activation ferritic-martensitic steels (RAFM-steels) are foreseen as structural materials in different blanket designs (HCLL, DCLL, WCLL) with Pb-15.7Li as breeding and partly also as cooling medium.
W. Krauss, S.-E. Wulf, J. Konys
doaj +1 more source

