Results 111 to 120 of about 979,586 (309)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Evaluación de familias de zapallo (Cucurbita moschata Duch.) seleccionadas por mayor contenido de materia seca en el fruto y otras características agronómicas Evaluation of squash (Cucurbita moschata Duch.) families selected for higher content of dry matter in the fruit and other agronomic traits

open access: yesActa Agronómica, 2010
Se evaluaron cuatro familias de hermanos completos de zapallo, Cucurbita moschata Duch, provenientes de dos ciclos de estabilización genética mediante cruzamientos fraternales y seleccionadas por mayor contenido de materia seca (MS) en el fruto y buenas ...
Dora Enith Tobar Tosse   +2 more
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Privatised provision of essential plant breeding infrastructure [PDF]

open access: yes
As private plant breeding replaces public programs, the efficient provision and utilisation of key enabling technologies for crop breeding, which are largely knowledge based and provide the foundation for variety improvement, might be at risk. Typically,
Lindner, Robert K.
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

‘Arkhat’ - a new spring soft wheat variety for the conditions of Povolzhie and Urals

open access: yesЗерновое хозяйство России, 2018
The article presents the data about a new spring soft wheat variety ‘Arkhat’ which has a realized potential of productivity (5.5 t/ha) and can produce valuable grain.
V. G. Krivobochek   +2 more
doaj  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Model calculations concerning economic optimalization of AI-breeding with cattle [PDF]

open access: yes, 1975
The effect of costs on the optimum breeding plan for selection for milk traits and the profitability of performance-test selection according to meat production were studied, including the consequences of beef crossing.
Brascamp, E.W.
core  

The variety of spring soft wheat ‘Tulaykovskaya 108’

open access: yesЗерновое хозяйство России, 2018
The article presents the technology of development of the variety of spring soft wheat ‘Tulaykovskaya 108’. In the selection process we have managed realizing the tasks appeared in the selection of parental forms.
V. V. Syukov   +2 more
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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