Results 111 to 120 of about 842,561 (316)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Comparative estimation of spring forms of triticale according to some quantitative traits

open access: yesЗерновое хозяйство России
The study was conducted to estimate and select spring breeding and collection forms of triticale for hybridization based on the calculation of the contribution of quantitative traits to plant ear productivity and to grain nature weight.
P. I. Stepochkin, T. S. Bauer
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Studies on breeding shorebirds at Medusa Bay, Taimyr, in summer 2001 [PDF]

open access: yes, 2001
In the Summer of 2001 a combined Dutch-Russian expedition took place to the Willem Barentz field station at Medusa Bay near Dikson in north-western Taimyr. The expedition was organized by Alterra, the Working Group for International Waterbird and Wetland
Tulp, I., Schekkerman, H.
core  

WHEAT BREEDING [PDF]

open access: yesJournal of Heredity, 1915
n ...
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Molecular breeding [PDF]

open access: yes, 2017
Molecular Breeding is an international journal focused on applications of plant molecular biology: research most likely leading to practical applications with demonstrable benefits for farmers, the seed and processing industries, the environment and the ...
TUBEROSA, ROBERTO   +2 more
core  

Evaluación de familias de zapallo (Cucurbita moschata Duch.) seleccionadas por mayor contenido de materia seca en el fruto y otras características agronómicas Evaluation of squash (Cucurbita moschata Duch.) families selected for higher content of dry matter in the fruit and other agronomic traits

open access: yesActa Agronómica, 2010
Se evaluaron cuatro familias de hermanos completos de zapallo, Cucurbita moschata Duch, provenientes de dos ciclos de estabilización genética mediante cruzamientos fraternales y seleccionadas por mayor contenido de materia seca (MS) en el fruto y buenas ...
Dora Enith Tobar Tosse   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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