Results 101 to 110 of about 4,264 (289)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Tritium breeding capability of water cooled ceramics breeder blanket with different container designs

open access: yes, 2018
Water cooled ceramic breeder (WCCB) blanket has been considered as the primary design in Japan. There are many thin cooling pipes in the blanket and internal pressure would be applied to the blanket by the pipe rupture. A number of efforts have been made
河村, 繕範   +23 more
core  

Neutronics analysis of spin-polarized fuel in spherical tokamaks

open access: yesNuclear Fusion
The effect of spin-polarized deuterium–tritium fuel on the blanket, magnets, and surrounding structures is analyzed for a spherical tokamak fusion power plant.
Jin Whan Bae   +7 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Development of water-cooled cylindrical blanket in JA DEMO

open access: yesNuclear Fusion
The concept of the tritium breeding blanket for Japan’s DEMOnstration fusion reactor (JA DEMO) has been developed with pressure tightness against in-box loss-of-coolant accidents based on a water-cooled solid breeder concept.
Someya Youji   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

High-dose neutron irradiation of beryllium and titanium beryllide: Summary and outlook

open access: yesNuclear Materials and Energy
The irradiation experiment conducted in the HFR material testing reactor, under conditions simulating the operating environment of the DEMO breeding blanket, along with subsequent post-irradiation examinations (PIEs) of irradiated beryllium-based ...
Vladimir Chakin   +15 more
doaj   +1 more source

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