Results 51 to 60 of about 22,199 (300)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Main Nuclear Responses of the DEMO Tokamak with Different In-Vessel Component Configurations
Applied SciencesResearch and development of the DEMOnstration power plant (DEMO) breeder blanket (BB) has been performed in recent years based on a predefined DEMO tritium breeding ratio (TBR) requirement, which determines a loss of wall surface due to non-breeding in ...
Jin Hun Park, Pavel Pereslavtsev
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Nuclear Engineering and TechnologyFusion reactors produce high-energy neutrons through the Deuterium-Tritium (DT) reaction. The long-term performance verification and structural integrity assessment of the breeding blanket under continuous plasma operation are essential for the ...
Hyoseong Gwon +3 more
doaj +1 more source
Conceptual design of solid-type Pb x Li y eutectic alloy breeding blanket for CFETR
Nuclear Fusion, 2023 As a key component of the Chinese Fusion Engineering and Test Reactor (CFETR), the blanket is responsible for tritium breeding, neutron shielding and energy conversion.
K. Jiang, Q. Wu, L. Chen, S. Liu
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ecology and Society, 2016 Emerging infectious diseases are a growing concern in wildlife conservation. Documenting outbreak patterns and determining the ecological drivers of transmission risk are fundamental to predicting disease spread and assessing potential impacts on ...
Samuel A. Iverson +4 more
doaj +1 more source
The use of zirconium hydride blankets in a minor actinide thorium burner sodium-cooled reactor for void coefficient control with particular reference to UK's plutonium disposition problem [PDF]
, 2015 The use of zirconium hydride (Th–ZrH1.6) blankets in a thorium-fuelled sodium-cooled reactor for void reactivity control with particular reference to UK's plutonium disposition problem is proposed and considered.
Arias, FJ, Parks, GT
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source