Results 61 to 70 of about 22,173 (305)

Progress report no. 4 [PDF]

open access: yes, 1973
Statement of responsibility on title-page reads: editors: M.J. Driscoll, D.D. Lanning, I. Kaplan, A.T. Supple ; contributors: A. Alvim, G.J. Brown, J.K. Chan, T.P. Choong, M.J. Driscoll, G. A. Ducat, I.A. Forbes, M.V. Gregory, S.Y. Ho, C.M. Hove, O.
Alvim, Antonio Carlos Marques   +21 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Systematic description of 6Li(n, n')6Li* $\to$ d + $\alpha$ reactions with the microscopic coupled-channels method

open access: yes, 2011
We investigate $^6$Li($n$, $n'$)$^6$Li$^*$ $\to$ $d$ + $\alpha$ reactions by using the continuum-discretized coupled-channels method with the complex Jeukenne-Lejeune-Mahaux effective nucleon-nucleon interaction.
Chiba, S.   +4 more
core   +1 more source

Timing as a sexually selected trait: the right mate at the right moment [PDF]

open access: yes, 2017
Sexual selection favours the expression of traits in one sex that attract members of the opposite sex for mating. The nature of sexually selected traits such as vocalization, colour and ornamentation, their fitness benefits as well as their costs have ...
Buck, C. Loren   +7 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Uncertainty assessment methodologies applied to Tritium production in fusion lithium breeding blankets [PDF]

open access: yes, 2011
- Need of Tritium production - Neutronic objectives - The Frascati experiment - Measurements of Tritium ...
Cabellos de Francisco, Oscar Luis   +2 more
core  

The use of zirconium hydride blankets in a minor actinide thorium burner sodium-cooled reactor for void coefficient control with particular reference to UK's plutonium disposition problem [PDF]

open access: yes, 2015
The use of zirconium hydride (Th–ZrH1.6) blankets in a thorium-fuelled sodium-cooled reactor for void reactivity control with particular reference to UK's plutonium disposition problem is proposed and considered.
Arias, FJ, Parks, GT
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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