Results 111 to 120 of about 407,600 (313)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Genomics-assisted breeding – A revolutionary strategy for crop improvement

open access: yesJournal of Integrative Agriculture, 2017
Food shortages arise more frequently owing to unpredictable crop yield losses caused by biotic and abiotic stresses. With advances in molecular biology and marker technology, a new era of molecular breeding has emerged that has greatly accelerated the ...
Peng-fei LENG   +2 more
doaj   +1 more source

A breeding strategy for improving drought and salt tolerance of poplar based on CRISPR/Cas9. [PDF]

open access: yesPlant Biotechnol J, 2023
Zhang T   +11 more
europepmc   +1 more source

Lunar cycles of reproduction in the clown anemonefish Amphiprion percula: individual-level strategies and population-level patterns [PDF]

open access: yes, 2018
Lunar cycles of reproduction are a widespread phenomenon in marine invertebrates and vertebrates. It is common practice to infer the adaptive value of this behavior based on the population level pattern.
Seymour, Jeremiah R.
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Breeding goats for organic production in Germany [PDF]

open access: yes, 2001
With only 120,000 females (year 2000), goat keeping is a niche activity in animal husbandry in Germany. Most of the goats (about 90%) are kept on part-time farms.
Rahmann, Gerold
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Optimal Breeding Strategies for Calving Ease

open access: yesJournal of Dairy Science, 1994
Calving ease is of economic importance in dairy cattle and should be considered in breeding programs. Economic values of direct and maternal calving ease were derived based on cost-benefit analysis and gene flow methodology. Marginal returns from dystocia reduction in primiparous dams were -$43 per phenotypic standard deviation compared with $300 for ...
openaire   +2 more sources

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