Results 41 to 50 of about 122,547 (263)
Utilizing Genomic Selection for Wheat Population Development and Improvement
Agronomy, 2022 Wheat (Triticum aestivum L.) breeding programs can take over a decade to release a new variety. However, new methods of selection, such as genomic selection (GS), must be integrated to decrease the time it takes to release new varieties to meet the ...
Lance F. Merrick +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An Update on Genetic Resistance of Chickpea to Ascochyta Blight
Agronomy, 2016 Ascochyta blight (AB) caused by Ascochyta rabiei (Pass.) Labr. is an important and widespread disease of chickpea (Cicer arietinum L.) worldwide. The disease is particularly severe under cool and humid weather conditions.
Mamta Sharma, Raju Ghosh
doaj +1 more source
Breeding strategies for temperate hardwoods [PDF]
Forestry: An International Journal of Forest Research, 2005 Temperate hardwoods include both genera grown under traditional long-rotation silvicultural regimes, such as Fraxinus and Quercus , and those such as Eucalyptus or Salix grown as shortrotation plantations. Strategies for breeding temperate hardwoods have developed signifi cantly over the past 20 years, informed by conceptual, technological and ...
Burley, Jeffrey, Kanowski, Peter
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A trait dataset for Taiwan's breeding birds [PDF]
Biodiversity Data Journal, 2020 Pei-Yu Tsai +6 more
doaj +3 more sources
Genetic progress in traits of yield, phenology and morphology of common bean
Crop Breeding and Applied Biotechnology, 2008 The genetic progress achieved by the research institutions that registered common bean cultivars in the State of Rio Grande do Sul between 1998 and 2005 was estimated in traits of yield, Phenology and morphology of common bean, with the aim to orient ...
Nerinéia Dalfollo Ribeiro +4 more
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