Results 111 to 120 of about 766,120 (259)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Increased performance of sheep and goat value chains in Ethiopia through community-based sheep and goat breeding programs [PDF]

open access: yes, 2019
Poster prepared for a share fair, Addis Ababa, May ...
Rischkowsky, Barbara A.
core  

Genomic prediction of genotyped and non-genotyped Jeju black cattle using single- and multi-trait methods for carcass traits

open access: yesItalian Journal of Animal Science
Jeju black cattle (JBC) are recognised as one of Korea’s native breeds that are well-suited to the local environmental conditions and known for their excellent meat quality.
Md Azizul Haque   +4 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Exploring the genetic resources of yam in the Democratic Republic of Congo: implications for breeding

open access: yesFrontiers in Horticulture
IntroductionLandrace accession of yam species in the Democratic Republic of Congo (DRC) represents a valuable genetic resource for yam breeding programs. These accessions possess traits such as stress resilience and desirable food quality attributes that
Idris Adejumobi   +10 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Citrus breeding for biotic and abiotic stress tolerances; new tools and strategies for biodiversity Mobilization : S04T01 [PDF]

open access: yes, 2013
Citrus industry is affected worldwide by several fungal, bacterial and viral diseases. Some production areas also suffer of strong abiotic constraints such as water deficit, salt stress and iron chlorosis. Resistance or tolerance traits for most of these
Ollitrault, Patrick
core  

Comparison of accuracy of breeding value for cow from three methods in Hanwoo (Korean cattle) population. [PDF]

open access: yesJ Anim Sci Technol, 2023
Lee HS   +11 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Optimal Search in Ex situ Collections of Wheat Genetic Resources [PDF]

open access: yes
This paper develops a theoretical model for analyzing gene bank management decisions regarding the search for traits of economic value in ex situ collections of wheat.
Gollin, Douglas   +2 more
core   +1 more source

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