Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Case Study on Increasing Breeding Value Estimation Reliability of Reproductive Traits in Serbian Highly Prolific Large White and Landrace Sows. [PDF]
Stojiljković N +6 more
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Estimated Breeding Values of Aberdeen-Angus Cattle Breed
Anuarbek Temirbekovich Bissembayev +8 more
openaire +1 more source
A genomic estimated breeding value-assisted reduction method of single nucleotide polymorphism sets: a novel approach for determining the cutoff thresholds in genome-wide association studies and best linear unbiased prediction. [PDF]
Lee YS, Oh JD, Lee JY, Shin D.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Оценка урожайности перспективных линий сои селекции ФГБНУ «АНЦ «Донской»
The estimation of productivity of the promising lines of soybean developed by the FSBSI “ARC ‘Donskoy” The article presents the material concerning the estimation of productivity of the promising lines of soybean developed by the FSBSI “ARC ‘Donskoy ...
A. R. Ashiev +3 more
doaj
Verifying the Breeding Value of A Rare Haplotype of Chalk7, GS3, and Chalk5 to Improve Grain Appearance Quality in Rice. [PDF]
Wang D +5 more
europepmc +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Evaluation of breeding values of sires and cows in dairy breeds [PDF]
V. O. Danshin +2 more
openaire +1 more source

