Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Genetic evaluation of flowering, maturity time and productivity in almond (Prunus dulcis): heritability estimates and breeding value predictions. [PDF]
Gómez-Abajo MDM +4 more
europepmc +1 more source
The effects of birth weight and estimated breeding value for protein deposition on nitrogen efficiency in growing pigs. [PDF]
Van der Peet-Schwering CMC +5 more
europepmc +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High-Accuracy Breeding Value Prediction Without Compromising Embryo Survival. [PDF]
Zhang J +12 more
europepmc +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Unbiased estimation of the breeding value of bulls [PDF]
openaire +4 more sources
Optimization of Genomic Breeding Value Estimation Model for Abdominal Fat Traits Based on Machine Learning. [PDF]
Chen H +10 more
europepmc +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
The value of texture in berries breeding
Texture is one of the most important traits for breeding activity in berries, considering its impact on consumer appreciation and postharvest performance. Since berries are consumed as a whole fresh fruit, the knowledge about its physiological dynamic over the different phases of fruit development is a crucial aspect in order to identify the most ...
Giongo, L. +6 more
openaire +1 more source

