Results 81 to 90 of about 6,343,230 (306)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Behaviour of kittiwakes during the breeding season: relationships with nest density and breeding success [PDF]

open access: yes, 2000
Activity budgets for kittiwakes at the nest site were determined for colonies on Tyneside during the pre-laying period in 1996 and for the Skomer Island colony during the pre-laying period in 1998 and for incubation and chick rearing in 1997 and 1998 ...
Nickerson, Michelle
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

COMBINING ABILITY OF SELECTED DESSERT STRAWBERRY CULTIVARS WITH DIFFERENT FRUIT RIPENING PERIODS

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2014
The subjects of the study were the strawberry hybrids of the F1 generation, derived from the crossing made between eight cultivars: ‘Darselect’, ‘Selvik’, ‘Elianny’, ‘Susy’, ‘Salsa’, ‘Albion’, ‘Charlotte’ and ‘Filon’ in an incomplete diallel mating ...
Agnieszka Masny   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ADAPTIVE CAPACITY AND BREEDING VALUE OF VEGETABLE VARIETIES OF PEAS COLLECTION

open access: yesОвощи России, 2015
Adaptive properties and selection value of vegetable pea collection based on «seed weight per plant» have been studied. The genotypes with high total and specific adaptive capacity, relative stability, and breeding value for multiple purposes have been ...
T. N. Abrosimova, A. N. Fadeeva
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Estimation of the breeding value of sport horses in the Czech Republic

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2004
The performance of 10671 horses in 10911 sport competitions was used to estimate the breeding value of the population of the Czech warm-blooded horses using the Best Linear Unibased Prediction method.
Iva Jiskrová
doaj   +1 more source

CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2021

open access: yes, 2021
The CGIAR Excellence in Breeding (EiB) Platform is accelerating the modernization of crop breeding programs that serve farmers in low- and middle-income countries.
CGIAR Excellence in Breeding Platform
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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