Results 91 to 100 of about 261,629 (263)

Implementation of SCC breeding values in Italian Jersey breed

open access: yes, 2021
In the framework of the LATTeco project, ANAFIJ (Associazione Nazionale Allevatori della Razza Frisona e Jersey Italiana) has been working on improving animal welfare, biodiversity and sustainability. Focusing on animal welfare, ANAFIJ has implemented a genetic evaluation for somatic cell count (SCC) in the Italian Jersey population.
Anna Fabris, Mauro Penasa, Tania Bobbo
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Trends in Breeding Value and Production

open access: yesJournal of Dairy Science, 1977
Over 3.6 million first lactation records by cows on official test were studied. About 15.5 yr of data for six dairy breeds were represented. Sire breeding value was twice the sire's Modified Contemporary Deviation from the USDA Sire Summary. Sire breeding values for milk and fat of cows calving in the later years increased for all breeds but Ayrshires,
R.L. Powell, H.D. Norman, F.N. Dickinson
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Adaptive potential of spring covered oats (Avena sativa L.) according to green biomass under the conditions of Kirov Province

open access: yesТруды по прикладной ботанике, генетике и селекции
Background. Development of high-yielding cultivars with high quality of their products is one of the main tasks of plant breeders. Today, the most valuable cultivars are those with high adaptability to stressful conditions of cultivation.
E. N. Vologzhanina, G. A. Batalova
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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