Results 91 to 100 of about 6,343,230 (306)

Modelling Agricultural Systems: Applications to Livestock Breeding [PDF]

Traditionally the evaluation of animal genetic traits has focused primarily on production traits and the construction of selection indices. Selection indices, however, fail to consider the effect of management practices and the environment on ...
Hattam, Caroline
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Analysis of Czech cold-blooded horses: genetic parameters, breeding value and the influence of inbreeding depression on linear description of conformation and type characters

Czech Journal of Animal Science, 2011
Genetic parameters, breeding values and inbreeding depression for 22 linear type description of conformation and type characters and 4 body measurements were evaluated in a group of 1744 horses of three original cold-blooded breeds in the Czech Republic ...
L. Vostrý, Z. Čapková, J. Přibyl, K. Mach   +3 more
doaj   +1 more source

Innovations in the dairy chain: bio-economic analysis of novel breeding opportunities [PDF]

, 2011
In recent years, there has been a growing interest in the dairy sector to move from producing bulk dairy commodities towards producing specialized dairy products aimed at niche markets. Dairy farmers consider shifting from commodity milk to raw milk with
Demeter, R.M.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Estimation of genetic parameters for melanoma in the Old Kladruber horse

Czech Journal of Animal Science, 2012
The aim of this study was to assess the prevalence of melanoma to investigate a possible genetic variation of this trait in the Old Kladruber horse.
L. Vostrý, B. Hofmanová, H. Vostrá Vydrová, J. Přibyl, I. Majzlík   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Stability of Aberdeen Angus breeding values in the Czech Republic from 1997 to 2007

Czech Journal of Animal Science, 2011
We predict the stability of breeding values (BVs) for direct effect (DE) and maternal effect (ME) for live weights at 210 days of age in the entire population of purebred Aberdeen Angus cattle in the Czech Republic according to an increase of progeny ...
J. Ducháček, J. Přibyl, L. Stádník, L. Vostrý, J. Beran, L. Štolc   +5 more
doaj   +1 more source

The integration of ‘omic’ disciplines and systems biology in cattle breeding [PDF]

, 2010
peer-reviewedEnormous progress has been made in the selection of animals, including cattle, for specific traits using traditional quantitative genetics approaches.
Diskin, Michael G., M.G. Diskin, C.J. Creevey, D. Morris, Mullen, Michael P., D.P. Berry, S. Butler, Morris, Dermot G., M.P. Mullen, Meade, Kieran G, Butler, Stephen T., K.G. Meade, Creevey, Christopher J., Berry, Donagh   +13 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source