Results 81 to 90 of about 766,120 (259)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Consumer preferences for farmers’ varieties [PDF]
, 2018 Our food value chain is characterized by an ongoing concentration and standardization on all levels and a concomitant loss in diversity. Putting the breeding and multiplication of seeds back into the hands of farmers is one strategy to counteract this ...
Meier, Claudia, Oehen, Bernadette
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Faecal steroid measurements for the assessment of reproductive function in Japanese quail (Coturnix coturnix japonica) and kakapo (Strigops habroptilus) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University [PDF]
, 2002 The kakapo (Strigops habroptilus) is an endangered parrot endemic to New Zealand and little is known of its reproductive physiology. Reproductive function is conventionally determined by the measurement of reproductive steroids in plasma samples. This is
Hawke, Emma Jane
core
Biopower and an ecology of genes : seeing livestock as meat via genetics [PDF]
, 2015 This book chapter focuses on some of the implications of what has been represented as a radical change in livestock breeding for thinking about meat in relation to living farm animals: the use of genetic techniques in selecting breeding animals.
Holloway, Lewis
core +1 more source
Revista Brasileira de Zootecnia, 2007 Objetivou-se com esse trabalho comparar estimativas de componentes de variâncias obtidas por meio de modelos lineares mistos Gaussianos e Robustos, via Amostrador de Gibbs, em dados simulados.
Idalmo Garcia Pereira +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Czech Journal of Animal Science, 2011 Genetic parameters, breeding values and inbreeding depression for 22 linear type description of conformation and type characters and 4 body measurements were evaluated in a group of 1744 horses of three original cold-blooded breeds in the Czech Republic ...
L. Vostrý +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Evaluation of Naked Barley Landraces for Agro-morphological Traits [PDF]
, 2020 Naked barley (Hordeum vulgare var. nudum L.) is a traditional, culturally important, climate-resilient winter cereal crop of Nepal. Evaluation of the naked barely genotypes for yield and disease is fundamental for their efficient utilization in plant ...
Ghimire, K. H. (Krishna) +2 more
core