Results 41 to 50 of about 1,682 (166)
Inhalation toxicity of brevetoxin 3 in rats exposed for 5 days
, 2004 Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis. Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf.
McDonald, Jacob +11 more
core +1 more source
Enantioselective Total Synthesis of Brevetoxin A: Unified Strategy for the B, E, G, and J Subunits [PDF]
, 2009 Brevetoxin A is a decacyclic ladder toxin that possesses five-,six-, seven-, eight-, and nine-membered oxacycles, as well as 22 tetrahedral stereocenters.
Kyle A. Emmitte +13 more
core +1 more source
A Highly Convergent Approach to Brevetoxin A [PDF]
, 2007 Through optimized, scaled-up routes to the G and J rings of brevetoxin A, a convergent strategy based upon a Horner-Wadsworth-Emmons coupling reaction completed the GHIJ fragment.
Zuccarello, J. Lucas
core +1 more source
Convergent, Stereoselective Synthesis of the GHIJ Fragment of Brevetoxin A
, 2016 A stereoselective synthesis of the GHIJ fragment of brevetoxin A utilizing a convergent assembly strategy is described. Glycolate alkylation, ring-closing metathesis, and Hosomi−Sakurai reactions were central operations in the construction of the G ring ...
Michael T. Crimmins (1317639) +3 more
core +2 more sources
Toxins, 2023 Algal toxins pose a serious threat to human and coastal ecosystem health, even if their potential impacts are poorly documented in New Caledonia (NC).
Manoëlla Sibat +5 more
doaj +1 more source
Earth and Space Science, Volume 13, Issue 5, May 2026.Abstract We present a self‐supervised machine learning framework for detecting and mapping the severity and speciation of harmful algal blooms (HABs) using multi‐sensor satellite data. By fusing reflectance data from operational polar‐orbiting satellite‐based instruments (VIIRS, MODIS, OLCI, and OCI) with TROPOMI solar‐induced fluorescence (SIF), our ...
Nicholas J. LaHaye +2 more
wiley +1 more source
Ladder-Shaped Ion Channel Ligands: Current State of Knowledge
Marine Drugs, 2017 Ciguatoxins (CTX) and brevetoxins (BTX) are polycyclic ethereal compounds biosynthesized by the worldwide distributed planktonic and epibenthic dinoflagellates of Gambierdiscus and Karenia genera, correspondingly.
Yuri B. Shmukler, Denis A. Nikishin
doaj +1 more source
Chronic and punctuated changes in subtropical reef fish assemblages
Ecosphere, Volume 17, Issue 4, April 2026.Abstract Understanding temporal changes in marine biodiversity is crucial for managing and conserving reef ecosystems in the face of global environmental shifts. Although biodiversity changes at global and regional scales often differ, the role of subtropical systems in these patterns has been relatively understudied until recently.
Michael J. Schram +6 more
wiley +1 more source
Total Synthesis of Brevetoxin A [PDF]
, 2009 A total synthesis of brevetoxin A is reported. Two tetracyclic coupling partners, prepared from previously reported advanced fragments, were effectively united via a Horner—Wittig olefination.
Zuccarello, J. Lucas +6 more
core +1 more source
Interaction of a dinoflagellate neurotoxin with voltage-activated ion channels in a marine diatom [PDF]
PeerJ, 2018 Background The potent neurotoxins produced by the harmful algal bloom species Karenia brevis are activators of sodium voltage-gated channels (VGC) in animals, resulting in altered channel kinetics and membrane hyperexcitability.
Sheila A. Kitchen +2 more
doaj +2 more sources