Results 61 to 70 of about 1,646 (159)
Limnology and Oceanography: Methods, Volume 24, Issue 1, January 2026.Abstract Curcumin, a natural plant product derived from Curcuma longa, was assessed as a mitigation technique against the toxic bloom‐forming dinoflagellate Karenia brevis in two mesocosm experiments taking place in 2022 and 2024. In these experiments, curcumin was applied at a dosage of 5 mg L−1 to K.
Victoria Devillier +6 more
wiley +1 more source
A New Cytotoxicity Assay for Brevetoxins Using Fluorescence Microscopy
Marine Drugs, 2014 Brevetoxins are a family of ladder-framed polyether toxins produced during blooms of the marine dinoflagellate, Karenia brevis. Consumption of shellfish or finfish exposed to brevetoxins can lead to the development of neurotoxic shellfish poisoning.
Jennifer R. McCall +2 more
doaj +1 more source
An ecological framework for microbial metabolites in the ocean ecosystem
Limnology and Oceanography Letters, Volume 10, Issue 5, Page 636-659, September 2025.Abstract The ocean microbe‐metabolite network involves thousands of individual metabolites that encompass a breadth of chemical diversity and biological functions. These microbial metabolites mediate biogeochemical cycles, facilitate ecological relationships, and impact ecosystem health. While analytical advancements have begun to illuminate such roles,
Bryndan P. Durham +24 more
wiley +1 more source
Die Chemie und Biologie der Tetrodotoxin Naturstofffamilie
Angewandte Chemie, Volume 137, Issue 35, August 25, 2025.Tetrodotoxin ist vor allem als das Gift des Kugelfisches bekannt, einer Delikatesse in der japanischen Küche. Seine Toxizität beruht auf der selektiven Blockade von NaV Kanälen, wie am Beispiel der NaV1.7 Pore dargestellt, wobei das DEKA Motiv hervorgehoben ist, das für die Durchlässigkeit von Natriumionen verantwortlich ist.
Benedikt Nißl +6 more
wiley +1 more source
Marine Drugs, 2022 N-methyl-D-aspartate (NMDA) receptors play a critical role in activity-dependent dendritic arborization, spinogenesis, and synapse formation by stimulating calcium-dependent signaling pathways.
Suneet Mehrotra +3 more
doaj +1 more source
The Chemistry and Biology of the Tetrodotoxin Natural Product Family
Angewandte Chemie International Edition, Volume 64, Issue 35, August 25, 2025.Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Benedikt Nißl +6 more
wiley +1 more source
Marine Drugs, 2016 Voltage-gated sodium channels (VGSCs) are responsible for the generation of the action potential. Among nine classified VGSC subtypes (Nav1.1–Nav1.9), Nav1.7 is primarily expressed in the sensory neurons, contributing to the nociception transmission ...
Fang Zhao +6 more
doaj +1 more source
Semisynthesis of S-Desoxybrevetoxin-B2 and Brevetoxin-B2, and Assessment of Their Acute Toxicities
, 2016 Brevetoxins are neurotoxins associated with blooms of marine algae such as Karenia brevis and can accumulate in the marine food chain, causing intoxication of marine animals and people consuming seafood.
John S. Ramsdell (60818) +7 more
core +2 more sources
Food Risk Assess Europe, Volume 3, Issue 2, April 2025.Abstract In France, the presence of marine microalgae of the genus Ostreopsis has been identified repeatedly on the Mediterranean coast for several years, whereas on the French Basque coasts its presence is much more recent. In the summers of 2021 and 2022, major Ostreopsis flowering episodes were reported on the Basque coast, resulting in several ...
Rodolphe Lemée +73 more
wiley +1 more source
Further Insights into Brevetoxin Metabolism by de Novo Radiolabeling
Toxins, 2014 The toxic dinoflagellate Karenia brevis, responsible for early harmful algal blooms in the Gulf of Mexico, produces many secondary metabolites, including potent neurotoxins called brevetoxins (PbTx).
Kevin Calabro +7 more
doaj +1 more source