Results 61 to 70 of about 2,771 (230)
Convergent, Stereoselective Synthesis of the GHIJ Fragment of Brevetoxin A
A stereoselective synthesis of the GHIJ fragment of brevetoxin A utilizing a convergent assembly strategy is described. Glycolate alkylation, ring-closing metathesis, and Hosomi−Sakurai reactions were central operations in the construction of the G ring ...
Michael T. Crimmins (1317639) +3 more
core +2 more sources
Regular occurrence of brevetoxin-producing toxic phytoplankton in commercial shellfishery areas poses a significant risk to shellfish consumer health. Brevetoxins and their causative toxic phytoplankton are more limited in their global distribution than
Andrew D. Turner +6 more
doaj +1 more source
Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish. [PDF]
Ciguatera fish poisoning is an illness suffered by > 50,000 people yearly after consumption of fish containing ciguatoxins (CTXs). One of the current methodologies to detect ciguatoxins in fish is a radiolabeled receptor binding assay (RBA(R)).
D Ransom Hardison +11 more
doaj +1 more source
In recent decades, more than 130 potentially toxic metabolites originating from dinoflagellate species belonging to the genus Karenia or metabolized by marine organisms have been described.
Vincent Hort +4 more
doaj +1 more source
The marine toxins known generically as brevetoxins, as well as their structural relative ciguatoxin, are known as polyether ladder toxins, and bind uniquely to site 5 of the voltage-sensitive sodium channel. Rat brain synaptosome binding data show similarities in binding affinity for brevetoxins having the same structural (ladder) backbone, but ...
R E, Gawley +3 more
openaire +2 more sources
Brevetoxin in two planktivorous fishes after exposure to Karenia brevis: implications for food-web transfer to bottlenose dolphins [PDF]
Brevetoxin uptake was analyzed in 2 common planktivorous fish that are likely foodweb vectors for dolphin mortality events associated with brevetoxin-producing red tides.
Ramsdell, John S., Hinton, Michael
core +1 more source
Brevetoxin: How Is It Made and Why [PDF]
Karenia brevis is the major harmful algal bloom-forming species in the Gulf of Mexico, and produces neurotoxins, known as brevetoxins, that cause large fish kills, neurotoxic shellfish poisoning, and human respiratory distress. Brevetoxins are polyethers
Thompson, Natalie
core +1 more source
Inhalation toxicity of brevetoxin 3 in rats exposed for 5 days
Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis. Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf.
McDonald, Jacob +11 more
core +1 more source
Abstract We present a self‐supervised machine learning framework for detecting and mapping the severity and speciation of harmful algal blooms (HABs) using multi‐sensor satellite data. By fusing reflectance data from operational polar‐orbiting satellite‐based instruments (VIIRS, MODIS, OLCI, and OCI) with TROPOMI solar‐induced fluorescence (SIF), our ...
Nicholas J. LaHaye +2 more
wiley +1 more source
Total Synthesis of Brevetoxin A
A total synthesis of brevetoxin A is reported. Two tetracyclic coupling partners, prepared from previously reported advanced fragments, were effectively united via a Horner−Wittig olefination.
Michael T. Crimmins (1317639) +6 more
core +2 more sources

