Results 1 to 10 of about 3,978 (197)
Research Progress in the Biosynthetic Mechanisms of Marine Polyether Toxins [PDF]
Marine Drugs, 2019 Marine polyether toxins, mainly produced by marine dinoflagellates, are novel, complex, and diverse natural products with extensive toxicological and pharmacological effects. Owing to their harmful effects during outbreaks of marine red tides, as well as
Xiukun Wan
exaly +7 more sources
Yessotoxins, a Group of Marine Polyether Toxins: an Overview [PDF]
Marine Drugs, 2008 Yessotoxin (YTX) is a marine polyether toxin that was first isolated in 1986 from the scallop Patinopecten yessoensis. Subsequently, it was reported that YTX is produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and ...
M Norte +2 more
exaly +11 more sources
Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins [PDF]
SciencePrymnesium parvum are harmful haptophyte algae that cause massive environmental fish kills. Their polyketide polyether toxins, the prymnesins, are among the largest nonpolymeric compounds in nature and have biosynthetic origins that have remained enigmatic for more than 40 years.
Timothy R Fallon +2 more
exaly +6 more sources
Boron’s Double Edge—Antibiotics, Toxins, and the Fine Line Between Them [PDF]
MoleculesBoron is a chemically distinctive bioelement whose electron-deficient structure enables reversible coordination with oxygen-rich functional groups such as diols and hydroxyls.
Valery M. Dembitsky +3 more
doaj +2 more sources
Brevetoxin Aptamer Selection and Biolayer Interferometry Biosensor Application [PDF]
ToxinsBrevetoxins (PbTxs) are very potent marine neurotoxins that can cause an illness clinically described as neurologic shellfish poisoning (NSP). These toxins are cyclic polyether in chemistry and have increased their geographical distribution in the past 2
Bo Hu +8 more
doaj +2 more sources
Apoptosis and Oxidative Stress in Human Intestinal Epithelial Caco-2 Cells Caused by Marine Phycotoxin Azaspiracid-2 [PDF]
ToxinsWhen humans consume seafood contaminated by lipophilic polyether phycotoxins, such as azaspiracids (AZAs), the toxins are mainly leached and absorbed in the small intestine, potentially causing intestinal damage.
Liye Zhao +4 more
doaj +2 more sources
Natural Polyether Ionophores and Their Pharmacological Profile
Marine Drugs, 2022 This review is devoted to the study of the biological activity of polyether ionophores produced by bacteria, unicellular marine algae, red seaweeds, marine sponges, and coelenterates.
Valery M. Dembitsky
doaj +1 more source
Gambierdiscus and Its Associated Toxins: A Minireview
Toxins, 2022 Gambierdiscus is a dinoflagellate genus widely distributed throughout tropical and subtropical regions. Some members of this genus can produce a group of potent polycyclic polyether neurotoxins responsible for ciguatera fish poisoning (CFP), one of the ...
Da-Zhi Wang, Ye-Hong Xin, Ming-Hua Wang
doaj +1 more source
Frontiers in Marine Science, 2021 The marine dinoflagellate genus Prorocentrum Ehrenberg comprises many species occupying primarily benthic or epiphytic habitats, particularly in tropical and sub-tropical waters.
Allan D. Cembella +11 more
doaj +1 more source
Marine Drugs, 2023 Tropical epibenthic dinoflagellate communities produce a plethora of bioactive secondary metabolites, including the toxins ciguatoxins (CTXs) and potentially gambierones, that can contaminate fishes, leading to ciguatera poisoning (CP) when consumed by ...
Alexander K. Leynse +4 more
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