Results 11 to 20 of about 3,978 (197)

Associated Bacteria and Their Effects on Growth and Toxigenicity of the Dinoflagellate Prorocentrum lima Species Complex From Epibenthic Substrates Along Mexican Coasts

Frontiers in Marine Science, 2020
The dinoflagellate genus Prorocentrum is globally represented by a wide variety of species found upon benthic and/or epiphytic substrates. Many epibenthic Prorocentrum species produce lipophilic polyether toxins, some of which act as potent protein ...
Ulrike I. Tarazona-Janampa, Ulrike I. Tarazona-Janampa, Ulrike I. Tarazona-Janampa, Allan D. Cembella, María C. Pelayo-Zárate, María C. Pelayo-Zárate, Silvia Pajares, Laura M. Márquez-Valdelamar, Yuri B. Okolodkov, Jan Tebben, Bernd Krock, Lorena M. Durán-Riveroll, Lorena M. Durán-Riveroll   +12 more
doaj   +1 more source

Automatic MS/MS Data Mining Strategy for Rapid Screening of Polyether Toxins Derived from <i>Gambierdiscus</i> Species. [PDF]

Anal Chem
Gambierdiscus is a primary producer of diverse polyether toxins that can biomagnify and transform within marine food webs, posing major risks to marine organisms and human health. Currently, many toxins derived from Gambierdiscus remain unidentified. Existing toxin analysis methodologies primarily rely on known toxins, limiting the representation of ...
Liu X, Xu C, Wu J, Foo YH, Zhou J, Wu B, Chan LL.   +6 more
europepmc   +3 more sources

Biological activities of aqueous and organic extracts from tropical marine sponges [PDF]

, 2010
We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested
Sepčić, Kristina, Kauferstein, Silke, Mebs, Dietrich, Turk, Tom   +3 more
core   +2 more sources

Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay.

PLoS ONE, 2016
BackgroundCiguatera is a circumtropical disease produced by polyether sodium channel toxins (ciguatoxins) that enter the marine food chain and accumulate in otherwise edible fish.
Richard J Lewis, Marco Inserra, Irina Vetter, William C Holland, D Ransom Hardison, Patricia A Tester, R Wayne Litaker   +6 more
doaj   +1 more source

Chemodiversity of Ladder-Frame Prymnesin Polyethers in Prymnesium parvum [PDF]

, 2016
Blooms of the microalga Prymnesium parvum cause devastating fish kills worldwide, which are suspected to be caused by the supersized ladder-frame polyether toxins prymnesin-1 and -2. These toxins have, however, only been detected from P.
Andersen, Nikolaj Gedsted, Blossom, Hannah Eva, Duus, Jens Øllgaard, Hansen, Per Juel, Larsen, Thomas Ostenfeld, Meier, Sebastian, Nielsen, Kristian Fog, Rasmussen, Silas Anselm   +7 more
core   +3 more sources

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins [PDF]

, 2018
In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for the detection of polyether toxins (prymnesins) associated with harmful algal blooms.
Field, Robert A., Hems, Edward S., Saalbach, Gerhard, Wagstaff, Ben A.   +3 more
core   +1 more source

Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates

Marine Drugs, 2010
Marine dinoflagellates are the single most important group of algae that produce toxins, which have a global impact on human activities. The toxins are chemically diverse, and include macrolides, cyclic polyethers, spirolides and purine alkaloids ...
Ralf Kellmann, Anke Stüken, Russell J. S. Orr, Helene M. Svendsen, Kjetill S. Jakobsen   +4 more
doaj   +1 more source

Fatty acid esters of azaspiracids identified in mussels (Mytilus edulis) using liquid chromatography-high resolution mass spectrometry

Toxicon: X, 2020
Azaspiracids (AZAs) are lipophilic polyether toxins produced by Azadinium and Amphidoma species of marine microalgae. The main dinoflagellate precursors AZA1 and AZA2 are metabolized by shellfish to produce an array of AZA analogues.
Elizabeth M. Mudge, Christopher O. Miles, William R. Hardstaff, Pearse McCarron   +3 more
doaj   +1 more source

Development of a New Monoclonal Antibody against Brevetoxins in Oyster Samples Based on the Indirect Competitive Enzyme-Linked Immunosorbent Assay

Foods, 2021
The consumption of shellfish contaminated with brevetoxins, a family of ladder-frame polyether toxins formed during blooms of the marine dinoflagellate Karenia brevis, can cause neurotoxic poisoning, leading to gastroenteritis and neurotoxic effects.
Xiya Zhang, Mingyue Ding, Chensi Zhang, Yexuan Mao, Youyi Wang, Peipei Li, Haiyang Jiang, Zhanhui Wang, Xuezhi Yu   +8 more
doaj   +1 more source

The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro [PDF]

, 2006
Brevetoxins (PbTxs) are highly potent trans-syn polyether neurotoxins produced during blooms of several species of marine dinoflagellates, most notably Karenia brevis. These neurotoxins act on voltage-sensitive sodium channels prolonging the active state.
A.J. Bourdelais, A.N. Sayer, Asai, Backer, Biswas, Bourdelais, Bourdelais, Charles, Clayson, D.G. Baden, Fairey, Gordon, Ito, J.E. Gibson, Jeglitsch, Kulagina, LePage, Lombet, Morita, Music, Perera, Poli, Q. Hu, Rein, Rooney, Sayer, Schantz, Schuster, Sokal, Trainer, Vieytes   +30 more
core   +1 more source