Results 11 to 20 of about 2,024 (141)
Research Progress in the Biosynthetic Mechanisms of Marine Polyether Toxins [PDF]
Marine Drugs, 2019 Marine polyether toxins, mainly produced by marine dinoflagellates, are novel, complex, and diverse natural products with extensive toxicological and pharmacological effects. Owing to their harmful effects during outbreaks of marine red tides, as well as
Xiukun Wan, Ge Yao, Jisheng Chen
exaly +5 more sources
Yessotoxins, a Group of Marine Polyether Toxins: an Overview [PDF]
Marine Drugs, 2008 Yessotoxin (YTX) is a marine polyether toxin that was first isolated in 1986 from the scallop Patinopecten yessoensis. Subsequently, it was reported that YTX is produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and ...
BEATRIZ Paz +2 more
exaly +8 more sources
Brevetoxin Aptamer Selection and Biolayer Interferometry Biosensor Application [PDF]
ToxinsBrevetoxins (PbTxs) are very potent marine neurotoxins that can cause an illness clinically described as neurologic shellfish poisoning (NSP). These toxins are cyclic polyether in chemistry and have increased their geographical distribution in the past 2
Bo Hu +8 more
doaj +3 more sources
Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins [PDF]
SciencePrymnesium parvum are harmful haptophyte algae that cause massive environmental fish kills. Their polyketide polyether toxins, the prymnesins, are among the largest nonpolymeric compounds in nature and have biosynthetic origins that have remained ...
Timothy R Fallon +2 more
exaly +4 more sources
Natural Polyether Ionophores and Their Pharmacological Profile
Marine Drugs, 2022 This review is devoted to the study of the biological activity of polyether ionophores produced by bacteria, unicellular marine algae, red seaweeds, marine sponges, and coelenterates.
Valery M. Dembitsky
doaj +2 more sources
Gambierdiscus and Its Associated Toxins: A Minireview
Toxins, 2022 Gambierdiscus is a dinoflagellate genus widely distributed throughout tropical and subtropical regions. Some members of this genus can produce a group of potent polycyclic polyether neurotoxins responsible for ciguatera fish poisoning (CFP), one of the ...
Da-Zhi Wang, Ye-Hong Xin, Ming-Hua Wang
doaj +2 more sources
Boron’s Double Edge—Antibiotics, Toxins, and the Fine Line Between Them [PDF]
MoleculesBoron is a chemically distinctive bioelement whose electron-deficient structure enables reversible coordination with oxygen-rich functional groups such as diols and hydroxyls.
Valery M. Dembitsky +3 more
doaj +2 more sources
Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function [PDF]
Marine Drugs, 2006 Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised by
Richard J. Lewis, Graham M. Nicholson
doaj +2 more sources
Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates
Marine Drugs, 2010 Marine dinoflagellates are the single most important group of algae that produce toxins, which have a global impact on human activities. The toxins are chemically diverse, and include macrolides, cyclic polyethers, spirolides and purine alkaloids ...
Ralf Kellmann +4 more
doaj +3 more sources
Toxins, 2018 Ciguatoxins are polyether marine toxins that act as sodium channel activators. These toxins cause ciguatera, one of the most widespread nonbacterial forms of food poisoning, which presents several symptoms in humans including long-term neurological ...
Juan Andrés Rubiolo +7 more
doaj +2 more sources