Results 21 to 30 of about 3,978 (197)

Radical Oxidative Cyclization of Spiroacetals to Bis-spiroacetals: An Overview

Molecules, 2004
The use of iodobenzene diacetate and iodine under photolytic conditions provides and efficient method for the oxidative cyclization of spiroacetals bearing an hydroxyalkyl side chain to bis-spiroacetals.
Margaret A. Brimble
doaj   +1 more source

Epoxide-Opening Cascades in the Synthesis of Polycyclic Polyether Natural Products [PDF]

, 2009
The structural features of polycyclic polyether natural products can, in some cases, be traced to their biosynthetic origin. However in case that are less well understood, only biosynthetic pathways that feature dramatic, yet speculative, epoxide-opening
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core   +1 more source

Liver genomic responses to ciguatoxin: evidence for activation of Phase I and Phase II detoxification pathways following an acute hypothermic response in mice [PDF]

, 2008
Ciguatoxins (CTX) are polyether neurotoxins that target voltage-gated sodium channels and are responsible for ciguatera, the most common fish-borne food poisoning in humans. This study characterizes the global transcriptional response of mouse liver to a
Bottein Dechraoui, Marie-Yasmine, Gordon, Christopher J., Levin, Edward D., Morey, Jeanine S., Ramsdell, John S., Rezvani, Amir H., Ryan, James C., Van Dolah, Frances M.   +7 more
core   +1 more source

Effect of different mixing and placement methods on the quality of MTA apical plug in simulated apexification model [PDF]

, 2017
It is necessary apical plug material to exhibit proper adaptation with the root canal walls. Presence of voids at the interface between the root canal wall and this material result in micro leakage, which might have a relationship with post treatment ...
Atharmoghaddam, Faezeh, Ghasemi, Negin, Janani, Maryam, Razi, Tahmineh   +3 more
core   +1 more source

A Review on the Biodiversity and Biogeography of Toxigenic Benthic Marine Dinoflagellates of the Coasts of Latin America

Frontiers in Marine Science, 2019
Many benthic dinoflagellates are known or suspected producers of lipophilic polyether phycotoxins, particularly in tropical and subtropical coastal zones. These toxins are responsible for diverse intoxication events of marine fauna and human consumers of
Lorena María Durán-Riveroll, Lorena María Durán-Riveroll, Allan D. Cembella, Yuri B. Okolodkov   +3 more
doaj   +1 more source

Painful toxins acting at TRPV1 [PDF]

, 2008
Many plant and animal toxins cause aversive behaviors in animals due to their pungent or unpleasant taste or because they cause other unpleasant senstations like pain.
Cromer, B, McIntyre, P
core   +1 more source

Association of the Toxigenic Dinoflagellate Alexandrium ostenfeldii With Spirolide Accumulation in Cultured Mussels (Mytilus galloprovincialis) From Northwest Mexico

Frontiers in Marine Science, 2018
Spirolides are polyether cyclic imines considered as “fast acting toxins.” Long-term human health consequences of spirolide ingestion are uncertain, and hence regulatory limits for human consumption have not been established.
Patricia Paredes-Banda, Ernesto García-Mendoza, Elizabeth Ponce-Rivas, Juan Blanco, Antonio Almazán-Becerril, Clara Galindo-Sánchez, Allan Cembella   +6 more
doaj   +1 more source

Neurotoxic shellfish poisoning [PDF]

, 2018
This is the final version of the article. Available from MDPI via the DOI in this recordNeurotoxic shellfish poisoning (NSP) is caused by consumption of molluscan shellfish contaminated with brevetoxins primarily produced by the dinoflagellate, Karenia ...
Fleming, LE, Hammond, R, Reich, A, Watkins, SM   +3 more
core   +1 more source

LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

Marine Drugs, 2020
Ciguatera poisoning is linked to the ingestion of seafood that is contaminated with ciguatoxins (CTXs). The structural variability of these polyether toxins in nature remains poorly understood due to the low concentrations present even in highly toxic ...
Fedor Kryuchkov, Alison Robertson, Christopher O. Miles, Elizabeth M. Mudge, Silvio Uhlig   +4 more
doaj   +1 more source

Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons

Toxins, 2018
Ciguatoxins are polyether marine toxins that act as sodium channel activators. These toxins cause ciguatera, one of the most widespread nonbacterial forms of food poisoning, which presents several symptoms in humans including long-term neurological ...
Juan Andrés Rubiolo, Carmen Vale, Andrea Boente-Juncal, Masahiro Hirama, Shuji Yamashita, Mercedes Camiña, Mercedes R. Vieytes, Luis M. Botana   +7 more
doaj   +1 more source