Results 21 to 30 of about 91,656 (195)

Radical Oxidative Cyclization of Spiroacetals to Bis-spiroacetals: An Overview

Molecules, 2004
The use of iodobenzene diacetate and iodine under photolytic conditions provides and efficient method for the oxidative cyclization of spiroacetals bearing an hydroxyalkyl side chain to bis-spiroacetals.
Margaret A. Brimble
doaj   +1 more source

Dihydrodinophysistoxin-1 produced by Dinophysis norvegica in the Gulf of Maine, USA and its accumulation in shellfish [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Deeds, J. R., Stutts, W. L., Celiz, M. D., MacLeod, J., Hamilton, A. E., Lewis, B. J., Miller, D.
Juliette L. Smith, McCarron, Pearse, Mary Dawn Celiz, Stutts, Whitney L., Stephen D. Archer, Shelley K. Lankford, Miller, David W., David W. Miller, Burnell, Craig A., Bryant J. Lewis, Archer, Stephen D., Borchert, Jerry, Amy E. Hamilton, Jill MacLeod, Kanwit, Kohl, Kulis, David M., Craig A. Burnell, Pearse McCarron, Lankford, Shelley K., Hamilton, Amy E., Jerry Borchert, Whitney L. Stutts, Lewis, Bryant J., Carlton D. Rauschenberg, Kohl Kanwit, Smith, Juliette L., David M. Kulis, MacLeod, Jill, Jonathan R. Deeds, Celiz, Mary Dawn, Deeds, Jonathan R., Rauschenberg, Carlton D.   +31 more
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A Review on the Biodiversity and Biogeography of Toxigenic Benthic Marine Dinoflagellates of the Coasts of Latin America

Frontiers in Marine Science, 2019
Many benthic dinoflagellates are known or suspected producers of lipophilic polyether phycotoxins, particularly in tropical and subtropical coastal zones. These toxins are responsible for diverse intoxication events of marine fauna and human consumers of
Lorena María Durán-Riveroll, Lorena María Durán-Riveroll, Allan D. Cembella, Yuri B. Okolodkov   +3 more
doaj   +1 more source

Association of the Toxigenic Dinoflagellate Alexandrium ostenfeldii With Spirolide Accumulation in Cultured Mussels (Mytilus galloprovincialis) From Northwest Mexico

Frontiers in Marine Science, 2018
Spirolides are polyether cyclic imines considered as “fast acting toxins.” Long-term human health consequences of spirolide ingestion are uncertain, and hence regulatory limits for human consumption have not been established.
Patricia Paredes-Banda, Ernesto García-Mendoza, Elizabeth Ponce-Rivas, Juan Blanco, Antonio Almazán-Becerril, Clara Galindo-Sánchez, Allan Cembella   +6 more
doaj   +1 more source

LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

Marine Drugs, 2020
Ciguatera poisoning is linked to the ingestion of seafood that is contaminated with ciguatoxins (CTXs). The structural variability of these polyether toxins in nature remains poorly understood due to the low concentrations present even in highly toxic ...
Fedor Kryuchkov, Alison Robertson, Christopher O. Miles, Elizabeth M. Mudge, Silvio Uhlig   +4 more
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Bacterial Toxins, Current Perspectives

, 2020
Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
core   +1 more source

Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons

Toxins, 2018
Ciguatoxins are polyether marine toxins that act as sodium channel activators. These toxins cause ciguatera, one of the most widespread nonbacterial forms of food poisoning, which presents several symptoms in humans including long-term neurological ...
Juan Andrés Rubiolo, Carmen Vale, Andrea Boente-Juncal, Masahiro Hirama, Shuji Yamashita, Mercedes Camiña, Mercedes R. Vieytes, Luis M. Botana   +7 more
doaj   +1 more source

Alternative method to detect compounds produced by Gambierdiscus spp.

Frontiers in Marine Science, 2014
Ciguatoxins (CTXs) and CTX precursors are produced by several Gambierdiscus spp. These polyether toxins are associated to ciguatera fish poisoning (CFP). In addition to CTX, maitotoxins (MTX) and gambierol are also produced by these dinoflagellates.
Jon Andoni Sánchez
doaj   +1 more source

Transcriptomic analysis of polyketide synthases in a highly ciguatoxic dinoflagellate, Gambierdiscus polynesiensis and low toxicity Gambierdiscus pacificus, from French Polynesia.

PLoS ONE, 2020
Marine dinoflagellates produce a diversity of polyketide toxins that are accumulated in marine food webs and are responsible for a variety of seafood poisonings.
Frances M Van Dolah, Jeanine S Morey, Shard Milne, André Ung, Paul E Anderson, Mireille Chinain   +5 more
doaj   +1 more source

Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function

Marine Drugs, 2006
Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised by
Richard J. Lewis, Graham M. Nicholson
doaj   +1 more source