Results 21 to 30 of about 1,879 (144)

LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

open access: yesMarine Drugs, 2020
Ciguatera poisoning is linked to the ingestion of seafood that is contaminated with ciguatoxins (CTXs). The structural variability of these polyether toxins in nature remains poorly understood due to the low concentrations present even in highly toxic ...
Fedor Kryuchkov   +4 more
doaj   +1 more source

Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons

open access: yesToxins, 2018
Ciguatoxins are polyether marine toxins that act as sodium channel activators. These toxins cause ciguatera, one of the most widespread nonbacterial forms of food poisoning, which presents several symptoms in humans including long-term neurological ...
Juan Andrés Rubiolo   +7 more
doaj   +1 more source

Transcriptomic analysis of polyketide synthases in a highly ciguatoxic dinoflagellate, Gambierdiscus polynesiensis and low toxicity Gambierdiscus pacificus, from French Polynesia.

open access: yesPLoS ONE, 2020
Marine dinoflagellates produce a diversity of polyketide toxins that are accumulated in marine food webs and are responsible for a variety of seafood poisonings.
Frances M Van Dolah   +5 more
doaj   +1 more source

Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation

open access: yesAngewandte Chemie, EarlyView.
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen   +17 more
wiley   +2 more sources

Alternative method to detect compounds produced by Gambierdiscus spp.

open access: yesFrontiers in Marine Science, 2014
Ciguatoxins (CTXs) and CTX precursors are produced by several Gambierdiscus spp. These polyether toxins are associated to ciguatera fish poisoning (CFP). In addition to CTX, maitotoxins (MTX) and gambierol are also produced by these dinoflagellates.
Jon Andoni Sánchez
doaj   +1 more source

Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function

open access: yesMarine Drugs, 2006
Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised by
Richard J. Lewis, Graham M. Nicholson
doaj   +1 more source

Polyether toxin analysis of the top minnow(Poecilia vitatta)

open access: yesFood and Agricultural Immunology, 1993
A detailed toxicity analysis was performed on the top minnow utilizing the stick‐enzyme immunoassay (S‐EIA), the mouse bioassay, the guinea pig atrium assay and fluorometric HPLC. The S‐EIA test indicated 96% of the samples tested contained polyether toxins. Mice injected with acetone extractions from top minnow displayed symptoms of toxicity while the
E. Titus   +3 more
openaire   +1 more source

Field‐Programmed Anisotropy in Magneto‐Piezoelectric Composites for Material‐Encoded Mechanoperception

open access: yesAdvanced Materials, EarlyView.
Field‐programmed anisotropy imparts material‐level intelligence to soft composites. Magnetic torque dynamics drive magneto‐piezoelectric nanowires from random dispersion into deterministic axial alignment. The resulting hierarchical percolation networks confine electromechanical coupling to specific axes and intrinsically decouple superposed force ...
Yubin Kim   +9 more
wiley   +1 more source

A New Cytotoxicity Assay for Brevetoxins Using Fluorescence Microscopy

open access: yesMarine Drugs, 2014
Brevetoxins are a family of ladder-framed polyether toxins produced during blooms of the marine dinoflagellate, Karenia brevis. Consumption of shellfish or finfish exposed to brevetoxins can lead to the development of neurotoxic shellfish poisoning.
Jennifer R. McCall   +2 more
doaj   +1 more source

Absolute Configuration at C45 in 45-Hydroxyyessotoxin, a Marine Polyether Toxin Isolated from Shellfish

open access: yesBioscience, Biotechnology, and Biochemistry, 2000
The marine polyether toxin, 45-hydroxyyessotoxin, was isolated together with yessotoxin from the scallop, Patinopecten yessoensis. The 45-hydroxy group in the side chain was esterified with (S)- and (R)-alpha-methoxyalpha-trifluoromethylphenylacetic acids (MTPA).
MOROHASHI, Akio   +3 more
openaire   +2 more sources

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