Results 91 to 100 of about 1,682 (166)
Development of Novel Liquid Chromatography-Electrospray Tandem Mass Spectrometry Approaches for the Structural Characterization of Brevetoxins Including in vitro Metabolites [PDF]
, 2007 Brevetoxins are natural neurotoxins that are produced by “red tide†algae. In this study, brevetoxin-1 and brevetoxin-2 were incubated with rat liver hepatocytes and rat liver microsomes, respectively.
Wang, Weiqun
core
Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer
, 2014 Brevetoxin B is a highly reactive molecule, due in part to an α,β-unsaturated aldehyde group at the terminal side chain, leading to metabolism by reduction, oxidation and conjugation. These reactions have little effect to reduce intrinsic activity at the
Henri, Jérôme +5 more
core +1 more source
, 2023 The northern quahog (Mercenaria mercenaria Linnaeus, 1758) is heavily valued for its ability to filter excess nutrients from marine ecosystems, and as a delicacy in the shellfish aquaculture industry.
Ponce, David
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Brevenal and β-naphtoyl-brevetoxin abolishes ciguatoxin-evoked release of catecholamines.
, 2013 Chromaffin cells were pre-treated (15 min) with increasing concentrations of either brevenal (A) or β-naphtoyl-brevetoxin (B) and subsequently exposed to indicated concentrations of P-CTX-1B, nicotine or vehicle alone as indicated in the figure, before ...
Frédéric A. Meunier (5653969) +9 more
core +1 more source
Harmful algal blooms (HAB’s) of the dinoflagellate Karenia brevis (Gymnodinium breve) are recurring events in the Gulf of Mexico (GOM) which have significant adverse human health, environmental and economic impacts.
Hardman, Ron C.
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Inhalation Toxicity of Brevetoxin 3 in Rats Exposed for Twenty-Two Days
, 2005 Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis . Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf.
Bourdelais, Andrea J +21 more
core +1 more source
, 1997 Brevetoxin-3 at nanomolar concentrations markedly enhanced spontaneous quantal transmitter release from neuromuscular junctions equilibrated in a Ca2+-free EGTA medium. After about 3 h, the sustained increase in miniature endplate potential frequency led
Colasante, C +5 more
core +1 more source
Brevetoxin: How Is It Made and Why [PDF]
, 2011 Karenia brevis is the major harmful algal bloom-forming species in the Gulf of Mexico, and produces neurotoxins, known as brevetoxins, that cause large fish kills, neurotoxic shellfish poisoning, and human respiratory distress. Brevetoxins are polyethers
Thompson, Natalie
core
, 2012 Values (mean calculations of all available assay data) are reported in ng brevetoxin-3 equiv./g or ng/mL. Data are median, quartile, and minimum/maximum values indicated by the midline, box, and whisker lines; respectively.
Joseph K. Gaydos (142699) +12 more
core +1 more source
Total Synthesis of Brevetoxin-B
, 2016 Brevetoxin-B (BTX-B), produced by the red tide organism, Gymnodium breve Davis, is the first member of marine polycyclic ethers to be structurally elucidated and one of the most potent neurotoxins. The structural feature is a trans-fused polycyclic ether
Goh Matsuo (2702941) +4 more
core +1 more source