Results 111 to 120 of about 735 (162)
Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer
, 2014 Brevetoxin B is a highly reactive molecule, due in part to an α,β-unsaturated aldehyde group at the terminal side chain, leading to metabolism by reduction, oxidation and conjugation. These reactions have little effect to reduce intrinsic activity at the
Henri, Jérôme +5 more
core +1 more source
ToxinsIn this report, we describe a fluorescent assay for the detection of six marine toxins in water. The mechanism of detection is based on a duplex-to-complex structure-switching approach.
Awatef Al-Tabban +5 more
doaj +1 more source
ToxicsBrevetoxins (PbTx) exert detrimental effects on marine organisms and humans, mainly through alterations in immune cell function. This study evaluated the immunotoxic potential of sublethal concentrations of PbTx-2 using the THP-1 human monocyte cell line
Ambbar Aballay-González +6 more
doaj +1 more source
Inhalation Toxicity of Brevetoxin 3 in Rats Exposed for Twenty-Two Days
, 2005 Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis . Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf.
Bourdelais, Andrea J +21 more
core +1 more source
Harmful algal blooms (HAB’s) of the dinoflagellate Karenia brevis (Gymnodinium breve) are recurring events in the Gulf of Mexico (GOM) which have significant adverse human health, environmental and economic impacts.
Hardman, Ron C.
core
Frontiers in ToxicologyAlthough adverse health effects from harmful algal bloom (HAB) toxins have been described since antiquity, the true worldwide incidence and disease burden has yet to be defined.
Brett Johnson +4 more
doaj +1 more source
Brevetoxin distribution in various sample types from stranded bottlenose dolphins in the 1999 UME.
, 2012 Values are reported in ng brevetoxin-3 equiv./g. Data are median, quartile, and minimum/maximum values indicated by the midline, box, and whisker lines; respectively. Note: ‘na’ denotes samples were not available for analysis and “
Joseph K. Gaydos (142699) +12 more
core +1 more source
Brevetoxin concentrations in various sample types from stranded bottlenose dolphins in the 2004 UME.
, 2012 Values (mean calculations of all available assay data) are reported in ng brevetoxin-3 equiv./g or ng/mL. Data are median, quartile, and minimum/maximum values indicated by the midline, box, and whisker lines; respectively. Note: “
Joseph K. Gaydos (142699) +12 more
core +1 more source
The Cardioprotective Potential of Marine Venom and Toxins
ToxinsCardiovascular disease (CVD) continues to be the primary cause of morbidity and mortality worldwide, underscoring the urgent need for novel therapeutic alternatives.
Virginia Heaven Mariboto Siagian +1 more
doaj +1 more source
, 2012 Data are expressed as ng brevetoxin/g and all analyses were conducted by ELISA or RBA.
Joseph K. Gaydos (142699) +12 more
core +1 more source