Briarane-Related Diterpenoids from Octocoral Briareum stechei [PDF]
Molecules, 2021 A known polyoxygenated briarane, briaexcavatolide P (1), was isolated from a Formosan octocoral Briareum stechei. Moreover, the same species B. stechei, collected from Okinawan waters, yielded three chlorine-containing briaranes, including two new ...
Thanh-Hao Huynh +9 more
doaj +5 more sources
Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum [PDF]
Scientific Reports, 2021 The four new briarane diterpenoids 2-butyryloxybriarane B-3 (2), 9-acetylbriarenolide S (3), briarenolide W (4), and 12-isobriarenolide P (5), along with briarane B-3 (1) and the five known diterpenes 6–10 were isolated from the gorgonian coral Briareum ...
Dawrin Pech-Puch +8 more
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Relative configuration of micrograms of natural compounds using proton residual chemical shift anisotropy [PDF]
Nature Communications, 2020 Determination of 3D molecular structures remains challenging for natural products or organic compounds available in minute amounts. Here, the authors determine the structure of complex molecules, including few micrograms of briarane B-3 isolated from ...
Nilamoni Nath +9 more
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Briarane Diterpenoids Isolated from Octocorals between 2014 and 2016 [PDF]
Marine Drugs, 2017 The structures, names, bioactivities, and references of 124 briarane-type natural products, including 66 new metabolites, isolated between 2014 and 2016 are summarized in this review article. All of the briarane diterpenoids mentioned in this review were
Yin-Di Su +6 more
doaj +5 more sources
Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum [PDF]
Marine Drugs, 2009 Two new briarane-related diterpenoids, designated as excavatoids E (1) andF (2), were isolated from the cultured octocoral Briareum excavatum. The structures ofcompounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes
Jyh-Horng Sheu +6 more
doaj +6 more sources
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin [PDF]
Journal of Biomedical Science, 2011 Background Skin is the largest organ in the body, and is directly exposed to extrinsic assaults. As such, the skin plays a central role in host defense and the cutaneous immune system is able to elicit specific local inflammatory and systemic immune ...
Wei Wen-Chi +7 more
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New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> [PDF]
Marine Drugs, 2012 Chemical investigation of <em>Junceella juncea</em> has resulted in the isolation of three new briaranes designated juncenolides M–O (<strong>1</strong>–<strong>3</strong>).
Tsong-Long Hwang +4 more
doaj +6 more sources
Briarenols I—K, New Anti-inflammatory 8,17-Epoxybriaranes from the Octocoral Briareum excavatum (Briareidae) [PDF]
Molecules, 2020 Five 8,17-epoxybriaranes, including three new compounds—briarenols I−K (1−3), along with two known analogues, briaexcavatolide P (4) and briaexcavatin P (5), were isolated from the octocoral Briareum excavatum.
Thanh-Hao Huynh +10 more
doaj +2 more sources
Marine diterpenoid targets STING palmitoylation in mammalian cells [PDF]
Communications Chemistry, 2023 Natural products are important sources of therapeutic agents and useful drug discovery tools. The fused macrocycles and multiple stereocenters of briarane-type diterpenoids pose a major challenge to total synthesis and efforts to characterize their ...
Wan-Chi Hsiao +9 more
doaj +2 more sources
11β,20β-Epoxybriaranes from the Gorgonian Coral Junceella fragilis (Ellisellidae) [PDF]
Marine Drugs, 2020 Two 11,20-epoxybriaranes, including a known compound, juncenolide K (1), as well as a new metabolite, fragilide X (2), have been isolated from gorgonian Junceella fragilis collected off the waters of Taiwan. The absolute configuration of juncenolide K (1)
Tung-Pin Su +9 more
doaj +2 more sources