Briaexcavatolide W, a New Diterpenoid from Briareum excavatum
A new briarane-type diteipenoid, briaexcavatolide W (1), has been isolated from the gorgonian coral Briareum excavatum. The structure was elucidated by spectroscopic methods.
Jyh‐Horng Sheu+4 more
semanticscholar +7 more sources
Briarenol B, a New Polyoxygenated Briarane from the Octocoral Briareum excavatum [PDF]
A new polyoxygenated briarane diterpenoid, briarenol B (1), was isolated from the octocoral Briareum excavatum and its structure determined from spectroscopic data.
Mu-Jang Li+6 more
semanticscholar +6 more sources
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin [PDF]
Background Skin is the largest organ in the body, and is directly exposed to extrinsic assaults. As such, the skin plays a central role in host defense and the cutaneous immune system is able to elicit specific local inflammatory and systemic immune ...
Wei Wen-Chi+7 more
doaj +7 more sources
Excavatolide C has oxidative-stress-dependent antiproliferative and apoptotic effects against breast cancer cells [PDF]
Background Triple negative breast cancer (TNBC) shows a poor response to targeted therapy drugs for non-triple-negative breast cancer (non-TNBC). Developing anticancer drugs that are effective for both TNBC and non-TNBC cells is necessary.
Jun-Ping Shiau+7 more
doaj +2 more sources
Research Progress on Natural Diterpenoids in Reversing Multidrug Resistance. [PDF]
Multidrug resistance (MDR) is one of the main impediments in successful chemotherapy in cancer treatment. Overexpression of ATP-binding cassette (ABC) transporter proteins is one of the most important mechanisms of MDR. Natural products have their unique
Deng ZF+6 more
europepmc +3 more sources
The application and sustainable development of coral in traditional medicine and its chemical composition, pharmacology, toxicology, and clinical research. [PDF]
This review discusses the variety, chemical composition, pharmacological effects, toxicology, and clinical research of corals used in traditional medicine in the past two decades.
Han M, Wang Z, Li Y, Song Y, Wang Z.
europepmc +3 more sources
Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health. [PDF]
The vast, untapped potential of the world’s oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as Nannochloropsis spp.
Gamberi C+10 more
europepmc +3 more sources
Cnidarians as a source of new marine bioactive compounds--an overview of the last decade and future steps for bioprospecting. [PDF]
Marine invertebrates are rich sources of bioactive compounds and their biotechnological potential attracts scientific and economic interest worldwide. Although sponges are the foremost providers of marine bioactive compounds, cnidarians are also being ...
Rocha J, Peixe L, Gomes NCM, Calado R.
europepmc +6 more sources
Tetrahydrofuran cembranoids from the cultured soft coral Lobophytum crassum. [PDF]
Three new cembranoids, culobophylins A–C (1–3), along with two known compounds (4 and 5) were isolated from the cultured soft coral Lobophytum crassum.
Lee NL, Su JH.
europepmc +4 more sources