Results 31 to 40 of about 5,842 (128)

Stereoselective Synthesis of Quaternary Carbons via the Dianionic Ireland-Claisen Rearrangement: An Approach to the Synthesis of Briarane Diterpenes [PDF]

open access: yes, 2012
Investigation of the dianionic Ireland-Claisen rearrangement has led to the development of a simple method to enantioselectively access quaternary carbon stereocenters via a chelated transition state.
Williams, Philip S.
core   +2 more sources

Diterpenos com atividade antitumoral frente células leucêmicas: uma revisão. [PDF]

open access: yes, 2014
The use of plants for medicinal purposes to treat, cure and prevent disease, is one of the olde st medicinal practices of mankind.
Moreira, Madson Matheus Barbosa.
core  

Total synthesis of (-)-mucocin and studies toward the asymmetric total synthesis of brianthein A [PDF]

open access: yes, 2007
A highly convergent asymmetric total synthesis of antitumor acetogenin natural product (-)-mucocin is described. This approach combined asymmetric glycolate aldol additions with ring-closing metatheses to construct cyclic ethers.
Zhang, Yan
core   +2 more sources

2,5-Cyclohexadienones as a Useful Launching Point for the Synthesis of the Briarane Diterpenoids and A Hypervalent Iodine-Mediated Synthesis of Oxazolines [PDF]

open access: yes, 2015
University of Minnesota Ph.D. dissertation.May 2015. Major: Chemistry. Advisor: Andrew Harned. 1 computer file (PDF); xix, 500 pages.The briarane diterpenoids are a large class of natural products derived from gorgonians and other corals from throughout
Moon, Nicholas
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Compostos de origem marinha com ação anti-inflamatória [PDF]

open access: yes, 2015
Dissertação de mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2015Durante milhares de anos, o ser humano tirou partido da capacidade da natureza para produzir remédios para tratar das doenças e outras ...
Rodrigues, Inna Glibka
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日本初記録の4 種のソフトコーラルの記載, 及 び琉球列島産浅海性ソフトコーラル類の一覧, およびホンクダヤギ属とクダヤギ属の分類に ついて [PDF]

open access: yes, 2017
So far, 121 species (including Briareum of the suborder Scleraxonia) of the shallow water soft corals had been found in the waters of the Ryukyu Archipelago. During 2011–2012, we surveyed the shallow water soft coral fauna from northern Motobu Peninsula (
Imahara, Yukimitsu   +7 more
core  

Nuevos compuestos de organismos marinos farmacológicamente activos [PDF]

open access: yes, 2013
[Resumen] Esta tesis doctoral describe diferentes métodos de aislamiento, estrategias para la determinación estructural, viabilidad de cultivo de esponjas y actividad farmacológica de una serie de productos naturales procedentes de organismos marinos ...
Nieto, Rosa M.
core   +1 more source

NATURAL PRODUCTS AS A SOURCE OF NEW THERAPIES FOR NEURODEGENERATIVE DISEASE AND EFFORTS TOWARD THE DEVELOPMENT OF A METABOLOMICS-BASED DRUG DISCOVERY PLATFORM [PDF]

open access: yes, 2010
Natural products have traditionally played an important role in drug discovery research. They have been particularly important in the search for therapies for neurodegenerative diseases.
Joyner, Phillip Matthew
core  

Leit að efnum með ónæmisbælandi áhrif úr íslenskum sjávarhryggleysingjum [PDF]

open access: yes, 2019
A substantial diversity of secondary metabolites from marine invertebrates has been described; however, only a few studies have investigated secondary metabolites of marine invertebrates collected in Icelandic waters. The unique marine environment around
Di, Xiaxia
core  

Structure and mechanism to function: allosteric activation of phosphomannomutase 1 and substrate selectivity in Hotdog Fold thioesterases [PDF]

open access: yes, 2016
Two superfamilies were used to explore the structure/function relationship as it pertains to enzyme specificity. The structures and mechanisms of phosphatases belonging to the Haloalkanoate Dehalogenase Superfamily (HADSF) and thioesterases of the ...
Ji, Tianyang
core   +1 more source

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