Results 31 to 40 of about 179,438 (314)

Bridge roughness index as an indicator of bridge dynamic amplification

open access: yes, 2006
The concept of a road roughness index for bridge dynamics is developed. The International Roughness Index (IRI) is shown to be very poorly correlated with bridge dynamic amplification as it takes no account of the location of individual road surface ...
O'Brien, Eugene J.   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Vehicle-bridge dynamic interaction using finite element modelling

open access: yes, 2010
First investigations on the dynamic response of bridges due to moving loads were motivated by the collapse of the Chester railway bridge in the UK in the middle of the 19th century.
Arturo Gonzalez, González, Arturo
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Reduction of bridge dynamic amplification through adjustment of vehicle suspension damping

open access: yes, 2007
This paper presents a novel approach to the reduction of short-span bridge dynamic responses to heavy vehicle crossing events. The reductions are achieved through adjustment of the vehicle suspension damping coefficient just before the crossing.
O\u27Brien, Eugene J.   +3 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Artificial Neural network-based prediction of SCF at the Intersection of CFST Y-joints

open access: yesAdvances in Bridge Engineering, 2022
Stress concentration factors (SCFs) are used to quantify the hot-spots stress in tubular joints with circular hollow section for fatigue assessment, which are always obtained by finite element analysis or specimens testing.
Lin Xiao   +3 more
doaj   +1 more source

OpenSeesPyView: Python programming-based visualization and post-processing tool for OpenSeesPy

open access: yesSoftwareX, 2023
This paper presents a newly developed visualization framework called OpenSeesPyView, a Python programming-based graphical user interface (GUI) for OpenSeesPy, a prevalent finite element solver in earthquake engineering.
Junjun Guo   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Sustainability of bridge maintenance [PDF]

open access: yes, 2019
Bridge maintenance activities are important to consider within sustainable development due to the cost and environmental impact associated with various maintenance activities. Comparisons have been made between different bridge structural forms, based on
Booth, CA   +9 more
core   +1 more source

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