Results 51 to 60 of about 137,456 (264)

CF60 Concrete Composition Design and Application on Fudiankou Xijiang Super Large Bridge

E3S Web of Conferences, 2018
Guangxi Wuzhou City Ring Road Fudiankou Xijiang super large bridge CF60 concrete is a new multi-phase composite high-performance concrete, this paper for the Fudiankou Xijiang bridge structure and characteristics of the project, in accordance with the ...
Qiu Yi Mei, Wen Sen Yuan, Chen Jun Xiang
doaj   +1 more source

Engineering bridging tradition: Ismaili Center Houston

Glass Structures & Engineering
Following London (1985), Vancouver (1985), Lisbon (1998), Dubai (2008), Dushanbe (2009) and Toronto (2014), the Ismaili Center Houston was established in 2025. Commissioned by the Aga Khan, spiritual leader of the Shia Ismaili Muslims, and designed by Farshid Moussavi Architecture, the Center functions as both a place of worship and a venue for ...
Tommaso Baudone, Jonas Hilcken, Felix Schmitt, Ladislaus Balint, Thomas Fritsche   +4 more
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

PyWindAM: A Python software for wind field analysis and cloud-based data management

SoftwareX
Given the substantial influence of wind loading on the structural performance of long-span bridges, continuous monitoring of wind field characteristics in their vicinity is paramount. PyWindAM is purpose-built web server software meticulously designed to
Nanxi Chen, Rujin Ma, Baixue Ge, Haocheng Chang   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Exploring a comprehensive knowledge map for bridge management research: a Delphi-enhanced scientometric analysis

Scientific Reports
Bridge infrastructure worldwide is aging, while demands for safety, sustainability, and cost-efficiency intensify challenges in bridge management (BM). This study develops a comprehensive knowledge map of BM through scientometric analysis, clarifying its
Peng Peng, Zuocai Wang, Peng Cui, Hongzhe Yue, Junfeng Yao, Sainan Lyu   +5 more
doaj   +1 more source

Impact spectra for eccentrically prestressed beam of bending-stretching effect under moving load

Resilient Cities and Structures
In this study, the impact behavior of an eccentrically prestressed simply-supported concrete beam of prophase bending-stretching retention subjected to a constant moving load is investigated for structure impact resilience evaluation.
Md Mahathe Hasan Toha, Zhi Sun, Chuhan Fan, Jianglin Xu   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Dynamic Responses of Long-Span Steel Truss Girder Cable-Stayed Bridge With a Single Pylon

Advances in Civil Engineering
The study investigates the seismic response of long-span single-tower and single-cable steel truss girder cable-stayed bridges, which structurally differ from traditional bridge types, and there is limited research on the influence of cable arrangement ...
Yong Zeng, Jiahao Wei, Yutong Zeng, Yunchuan Xiao, Hongwei Mao, Ming Huang, Zhongfu Xiang, Jianting Zhou   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source