Results 51 to 60 of about 951,547 (299)

A requirements engineering framework for integrated systems development for the construction industry [PDF]

, 2006
Computer Integrated Construction (CIC) systems are computer environments through which collaborative working can be undertaken. Although many CIC systems have been developed to demonstrate the communication and collaboration within the construction ...
Ahmed, V, Aouad, GF, Arayici, Y
core   +1 more source

Ear-clipping Based Algorithms of Generating High-quality Polygon Triangulation

, 2012
A basic and an improved ear clipping based algorithm for triangulating simple polygons and polygons with holes are presented. In the basic version, the ear with smallest interior angle is always selected to be cut in order to create fewer sliver ...
B Chazelle, GH Meisters, GT Toussaint, H ElGindy, H-YF Feng, J O’Rourke, JC Tipper, M Berg, M Held, MR Garey, R Seidel, X Kong   +11 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Track–Bridge Interaction of CWR on Chinese Large-Span Bridge of High-Speed Railway

Applied Sciences, 2022
The track–bridge interaction is a fundamental concern in the field of railway engineering, which plays an important role in the optimization design of railway bridges, especially for heavy-haul railway and high-speed railway bridges.
Bin Yan, Wenfei Kuang, Rui Gan, Haoran Xie, Jie Huang   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

CF60 Concrete Composition Design and Application on Fudiankou Xijiang Super Large Bridge

E3S Web of Conferences, 2018
Guangxi Wuzhou City Ring Road Fudiankou Xijiang super large bridge CF60 concrete is a new multi-phase composite high-performance concrete, this paper for the Fudiankou Xijiang bridge structure and characteristics of the project, in accordance with the ...
Qiu Yi Mei, Wen Sen Yuan, Chen Jun Xiang
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Charles Marcellis and Arthur Vierendeel: a century of Belgian bridge building (1835-1940) [PDF]

, 2012
The Belgian bridge builders Charles Marcellis (1798-1864) and Arthur Vierendeel (1852-1940) were jack-of-all-trades in the 19th century, but both were mostly known as bridge designers, trying to have a grip on new structural possibilities.
Bertels, Inge, Collette, Quentin, De Meyer, Ronald, Verswijver, Koen, Wouters, Ine   +4 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Study on terrain acquisition and processing technology of BDS-3 auxiliary mountain highway

Scientific Reports
The operation mode of UAV equipped with LiDAR can significantly reduce the efficiency and cost of highway terrain acquisition. At present, due to the complicated terrain and weak signal of mountain road, it is difficult to collect terrain data.
Guangtai Lin, Shijian Li, Jianjun Wang, Yongyou Li, Jingjun Qin, Rong Yan   +5 more
doaj   +1 more source