Results 61 to 70 of about 147,791 (261)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Dynamic Property Analysis of At-Ground Structure Under Moving Maglev Train

open access: yesUrban Rail Transit, 2017
In order to study the vertical coupling vibration of low–medium-speed Maglev train and at-ground structure system, the vertical coupling vibration model of low–medium-speed Maglev train-bridge system is established firstly based on the co-simulation of ...
Dangxiong Wang   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Investigation on Static Performance of Piers Assembled with Steel Cap Beams and Single Concrete Columns

open access: yesBuildings
To reduce the weight of prefabricated cap beams, a new type of hybrid pier with a steel cap beam and single concrete column with an innovative flange–rebar–ultra-high-performance concrete (UHPC) connection structure is proposed in this paper. Focusing on
Chong Shen   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Study on the impact of vehicle-induced vibration on the flexural behavior of UHPC joints in widened bridges

open access: yesUrban Lifeline
Bridge widening involves phased construction of adjacent structures to maintain uninterrupted traffic flow. This process exposes freshly placed longitudinal joints between staged deck constructions to vehicle-induced vibrations, potentially compromising ...
Jun Yang   +8 more
doaj   +1 more source

Improvement on Structural Forms of Pile Group Foundations of Deepwater Bridges

open access: yesShock and Vibration, 2019
As long-span cross-sea bridges extend to deeper sea areas, the bridge pile tends to increase in its slenderness ratio and becomes more susceptible to waves.
Enbo Yu   +4 more
doaj   +1 more source

Molecular Bridge Engineering for Tuning Quantum Electronic Transport and Anisotropy in Nanoporous Graphene. [PDF]

open access: yesJ Am Chem Soc, 2023
Moreno C   +8 more
europepmc   +1 more source

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