Results 71 to 80 of about 4,397,878 (335)

Charles Marcellis and Arthur Vierendeel: a century of Belgian bridge building (1835-1940) [PDF]

open access: yes, 2012
The Belgian bridge builders Charles Marcellis (1798-1864) and Arthur Vierendeel (1852-1940) were jack-of-all-trades in the 19th century, but both were mostly known as bridge designers, trying to have a grip on new structural possibilities.
Bertels, Inge   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Wind Monitoring of the Saylorville and Red Rock Reservoir Bridges with Remote, Cellular-Based Notifications, May 2012 [PDF]

open access: yes, 2012
Following high winds on January 24, 2006, at least five people claimed to have seen or felt the superstructure of the Saylorville Reservoir Bridge in central Iowa moving both vertically and laterally.

core  

Common Diseases of Road and Bridge Engineering and Application of Construction Treatment Technology

open access: yesFrontiers in Management Research, 2019
The purpose of this study is to understand the common diseases of road and bridge engineering and put forward the corresponding construction treatment technology.
Weiwei Li   +3 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Study on terrain acquisition and processing technology of BDS-3 auxiliary mountain highway

open access: yesScientific Reports
The operation mode of UAV equipped with LiDAR can significantly reduce the efficiency and cost of highway terrain acquisition. At present, due to the complicated terrain and weak signal of mountain road, it is difficult to collect terrain data.
Guangtai Lin   +5 more
doaj   +1 more source

Efficient Design Optimization of Cable-Stayed Bridges: A Two-Layer Framework with Surrogate-Model-Assisted Prediction of Optimum Cable Forces

open access: yesApplied Sciences
Cable-stayed bridges have commonly been built for crossing large-span obstacles, such as rivers, valleys, and existing structures. Obtaining an optimum design for a cable-stayed bridge is challenging, due to the large number of design variables and ...
Yuan Ma   +5 more
doaj   +1 more source

Comparison of bridge design in Malaysia between American codes and British codes [PDF]

open access: yes, 2005
The design of a highway bridge, like most any other civil engineering project, is dependant on certain standards and criteria. Naturally, the critical importance of highway bridges in a modern transportation system would imply a set of rigorous design ...
Wan Ahmad Kamal, Wan Ikram Wajdee
core  

Functionals of Brownian bridges arising in the current mismatch in D/A-converters

open access: yes, 2008
Digital-to-analog converters (DAC) transform signals from the abstract digital domain to the real analog world. In many applications, DAC's play a crucial role.
Heydenreich, Markus   +2 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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