Results 51 to 60 of about 545,733 (311)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
National Science Foundation Advisory Committee for Cyberinfrastructure Task Force on Campus Bridging Final Report [PDF]
, 2011 The mission of the National Science Foundation (NSF) Advisory Committee on Cyberinfrastructure (ACCI) is to advise the NSF as a whole on matters related to vision and strategy regarding cyberinfrastructure (CI).
ACCI Task Force on Campus Bridging
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2017 Since 2015 an increasing number of refugee children arrived in Germany. The federal government aims to facilitate these children’s access to German culture and language as early as possible. So-called Bridging Projects have been established to facilitate
Leyendecker, Prof. Dr. B.L. (Ruhr-Universität Bochum) +1 more
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Text as scene: discourse deixis and bridging relations [PDF]
, 2007 En este artículo se presenta un nuevo marco, “el texto como escena”, que establece las bases para la anotación de dos relaciones de correferencia: la deixis discursiva y las relaciones de bridging.
Taulé Delor, Mariona +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Applied SciencesThe study focused on isolating bioflocculant-producing microorganisms from poultry slaughterhouse wastewater (PSW). Microorganisms (n = 20) were isolated, and the D2 isolate, identified as Bacillus megaterium using 16S rDNA and RpoD (sigma 70), had ...
Melody Ruvimbo Mukandi +3 more
doaj +1 more source
Humanities & Social Sciences Communications, 2023 Conflict event datasets are used widely in academic, policymaking, and public spheres. Accounting for political violence across the world requires detailing conflict types, agents, characteristics, and source information.
Clionadh Raleigh +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source