Results 61 to 70 of about 545,733 (311)
Entre vanité et art poétique : l’esthétique du rien chez Graham Swift
Études Britanniques Contemporaines, 2012 As a metaphor of the disintegration into nothingness, the ashes in Last Orders bespeak the mere nothing of life (« it aint nothing at all ») and appear in numerous descriptions which can then be read as revisited vanitas paintings.
Christian Gutleben
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Teaching for transfer in EAP: hugging and bridging revisited
, 2015 While transfer of learning is an explicit goal of EAP, this end is sometimes neglected. To foster transfer, Salomon and Perkins (1989) advocated ‘hugging’ – creating learning experiences that are similar to the target applications – and ‘bridging ...
Green, Jonathan H.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Advanced Materials InterfacesSurface modification of polymeric materials to control their interaction with proteins has been studied extensively, leading to widespread bio‐applications.
Takanori Kishida
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Annual Review of Plant Biology, 2020 Zhi-Hong Xu is a plant physiologist who studied botany at Peking University (1959–1965). He joined the Shanghai Institute of Plant Physiology (SIPP), Chinese Academy of Sciences (CAS), as a graduate student in 1965. He recalls what has happened for the institute, during the Cultural Revolution, and he witnessed the spring of science eventually coming ...
openaire +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Bridge, Reverse Bridge, and Their Control
EntropyWe investigate the bridge problem for stochastic processes, that is, we analyze the statistical properties of trajectories constrained to begin and terminate at a fixed position within a time interval τ. Our primary focus is the time-reversal symmetry of these trajectories: under which conditions do the statistical properties remain invariant under the
Baldassarri, Andrea, Puglisi, Andrea
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Connectors and coordinators in natural resource governance: insights from Swiss water supply
Ecology and Society, 2018 Fragmentation across scales in natural resource governance can impede coordinated action and decrease innovation capacity. Bridging actors who connect others within governance networks helps to overcome this challenge.
Mario Angst +3 more
doaj +1 more source