Results 81 to 90 of about 545,733 (311)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Thrombolytic therapy with Revelisa in ischemic stroke: results of the PRIMA international multicenter observational study

Неврология, нейропсихиатрия, психосоматика
Thrombolytic therapy (TLT) of ischemic stroke (IS) with alteplase within the first 4.5 hours from the onset of symptoms is the most effective and proven method of treatment.Objective: to evaluate the safety and efficacy of TLT with Revelisa (alteplase ...
N. A. Shamalov, D. R. Khasanova, S. V. Marchenko, M. A. Soldatov, T. P Alekseeva, O. V. Androfagina, L. N. Antipova, L. I. Anishchenko, E. M. Beketova, A. A. Bulanov, A. V. Gerasimova, N. Kh. Gorst, A. G. Gutsalyuk, T. V. Demin, A. V. Dyudin, U. A. Yelemanov, A. R. Zakaryaeva, N. N. Zinovyeva, S. S. Ziborova, D. N. Kazakov, N. V. Komissarova, I. V. Korobeynikov, K. V. Korovashkova, E. L. Kuzmin, A. A. Kulesh, R. R. Kuliev, A. S. Lebedev, A. L. Lukyanov, V. I. Maksimov, O. I. Mikhaylenko, I. V. Moldavskaya, D. M. Murtazalieva, Yu. S. Mukhamadieva, V. N. Nesterova, D. G. Novikov, S. V. Platunova, E. P. Prudius, R. A. Rayemgulov, V. A. Saskin, A. V. Sinelshchikova, E. A. Strautmanis, V. S. Suryakhin, E. V. Tavlueva, Yu. A. Telyatnik, N. V. Halo, M. S. Cherepyansky, N. A. Marskaya   +46 more
doaj   +1 more source

Myocardial bridging

Brazilian Journal of Cardiovascular Surgery, 2015
Myocardial bridging is rare. Myocardial bridges are most commonly localized in the middle segment of the left anterior descending coronary artery. The anatomic features of the bridges vary significantly. Alterations of the endothelial morphology and the vasoactive agents impact on the progression of atherosclerosis of myocardial bridging.
openaire   +5 more sources

A Parallel between Brownian Bridges and Gamma Bridges

Publications of the Research Institute for Mathematical Sciences, 2004
Some properties of the Gamma bridges (obtained by conditioning the Gamma subordinator to take a given value at a given time) are investigated; similarities with the Brownian bridges are emphasized.
Yor, Marc, Emery, M.
openaire   +4 more sources

BRIDGING - Transfer digitaler Hochschulbildungskonzepte: Ein empirischer Zugang. Studienreport

, 2021
Im Rahmen des BMBF-Förderprogramms „Forschung zur digitalen Hochschulbildung – Innovationspotenziale Digitaler Hochschulbildung“ ging das Forschungsprojekt BRIDGING in zwei Projektphasen (01.01.2018 – 28.02.2019 sowie 01.03.2019 – 30.06.2020) in einer ...
Ladwig, Tina, Arndt, Christiane, Trümper, Stefanie, Knutzen, Sönke, Figura, Lisa   +4 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Key focal areas for bridging the fields of aging and disability: findings from the growing older with a disability conference

International Journal of Integrated Care, 2012
Based upon research presented at the 2011 Festival of International Conferences on Caregiving, Disability, Aging and Technology (FICCDAT)-and specifically the Growing Older with a Disability (GOWD) conference, this paper identifies areas where bridging ...
Vishaya Naidoo, Michelle Putnam, Andria Spindel   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

APHRON-BASED DRILLING FLUIDS: SOLUTION FOR LOW PRESSURE RESERVOIRS

Rudarsko-geološko-naftni Zbornik, 2009
Drilling wells throughout depleted or low pressure reservoirs requires low density drilling fluids, often with density less than water. Methods to reduce the density of drilling fluids have included mixing-in air or nitrogen. However, problems with these
Nediljka Gaurina-Međimurec , Borivoje Pašić   +1 more
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