Results 41 to 50 of about 138,897 (266)

Bright and Bright’s Disease

Res Medica, 2013
Richard Bright was born in 1789, the year in which George Washington became first President of the United States of America and France suffered a revolution. His father was a banker living in Bristol, an important city resting on the laurels of five centuries of maritime enterprise.
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Metrological characteristics of the Tensor-28 luminance meter [PDF]

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2007
The paper presents research results on metrological characteristics of the luminance meter "Tensor-28", designed to measure average screen brightness of picture tubes and other self-luminous surfaces.
Fodchuk I. M., Doktorovych I. V., Godovaniouk V. M., Butenko V. K., Yuriev V. G.   +4 more
doaj  

The effects of pre-treatment and consistency on treatment time and brightness of bagasse alkaline peroxide mechanical pulp [PDF]

تحقیقات علوم چوب و کاغذ ایران, 2012
Preparation and pre-treatment of raw material influences the pulp production time and color elimination.  Pulp consistency during the treatment also influences the color reaction.
Saeideh Sharifi, Ahmad reza Saraeyan, Hossein Resalati   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Papermaking Properties of Carpinus betulus with kraft, Soda and Soda-Urea Pulping Processes [PDF]

Iranian Journal of Wood and Paper Industries, 2013
This research was carried out in order to comparatively investigate the hornbeam kraft, soda and soda-urea papermaking properties. The selected treatment in kraft process had an average yield of 44.43% and kappa number of 23.75.
Rasoul Darstan, Majid Zabihzadeh, Noorodin Nazarnezhad   +2 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Light Extraction and Brightness Enhancement of Luminescent Rectangular Slabs

Advanced Photonics Research, 2022
The extraction efficiency and the brightness are critical parameters to increase the performance of luminescent rectangular slabs such as scintillators, luminescent concentrators, or diamonds with NV centers.
Pierre Pichon, Lisa Lopez, Maxime Nourry-Martin, Stéphane Darbon, Frederic Druon, Patrick Georges, François Balembois   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source