Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The effect of using deinked mixed office waste pulp on the properties of Alkaline Proxide Mechanical Pulp from cotton stalk [PDF]
The present study was carried out aiming to investigate the effect of using Deinked Mixed Office Waste Pulp (MOW) on the properties of Alkaline Peroxide Mechanical Pulp (APMP) from cotton stalk.
Mehrnoosh Tavakoli +3 more
doaj +1 more source
Perception of Brightness and Brightness Illusions in the Macaque Monkey [PDF]
Recent physiological studies show that neural responses correlated with the perception of brightness are found in cortical area V1 but not earlier in the visual pathway (Kayama et al., 1979; Reid and Shapley, 1989; Squatrito et al., 1990; Komatsu et al., 1996; Rossi et al., 1996; MacEvoy et al., 1998; Rossi and Paradiso, 1999; Hung et al., 2001 ...
Xin, Huang +2 more
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The effects of pre-treatment and consistency on treatment time and brightness of bagasse alkaline peroxide mechanical pulp [PDF]
Preparation and pre-treatment of raw material influences the pulp production time and color elimination. Pulp consistency during the treatment also influences the color reaction.
Saeideh Sharifi +2 more
doaj +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Papermaking Properties of Carpinus betulus with kraft, Soda and Soda-Urea Pulping Processes [PDF]
This research was carried out in order to comparatively investigate the hornbeam kraft, soda and soda-urea papermaking properties. The selected treatment in kraft process had an average yield of 44.43% and kappa number of 23.75.
Rasoul Darstan +2 more
doaj
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Light Extraction and Brightness Enhancement of Luminescent Rectangular Slabs
The extraction efficiency and the brightness are critical parameters to increase the performance of luminescent rectangular slabs such as scintillators, luminescent concentrators, or diamonds with NV centers.
Pierre Pichon +6 more
doaj +1 more source

