Results 71 to 80 of about 641,900 (344)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The sky brightness and transparency in i-band at Dome A, Antarctica
, 2011 The i-band observing conditions at Dome A on the Antarctic plateau have been investigated using data acquired during 2008 with the Chinese Small Telescope ARray. The sky brightness, variations in atmospheric transparency, cloud cover, and the presence of
A. M. Moore +33 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Effects of Starburst Activity on Low Surface Brightness Disk Galaxies
, 1998 Although numerous simulations have been done to understand the effects of intense bursts of star formation on high surface brightness galaxies, few attempts have been made to understand how localized starbursts would affect both the color and surface ...
Dalcanton J. J. +11 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Quantifying Color Variation: Improved Formulas for Calculating Hue with Segment Classification
Applications in Plant Sciences, 2014 Premise of the study: Differences in color form a major component of biological variation, and quantifying these differences is the first step to understanding their evolutionary and ecological importance.
Stacey D. Smith
doaj +1 more source
Utilization of Organic Complex of Glanapone Stab Rather than Sodium Silicate in Peroxide Bleaching of Mixed Hardwood CMP Pulp [PDF]
تحقیقات علوم چوب و کاغذ ایران, 2010 This research was accomplished in order to investigate the replacement of organic complex of Glanapone Stab with sodium silicate on optical properties of hardwood CMP pulp bleached by hydrogen peroxide.
Iman Akbarpour, Hossein Resalati
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source