Brillouin microscopy monitors rapid responses in subcellular compartments [PDF]
PhotoniXMeasurements and imaging of the mechanical response of biological cells are critical for understanding the mechanisms of many diseases, and for fundamental studies of energy, signal and force transduction.
Zachary N. Coker +6 more
doaj +4 more sources
Non-contact and label-free biomechanical imaging: Stimulated Brillouin microscopy and beyond [PDF]
Frontiers in Physics, 2023 Brillouin microscopy based on spontaneous Brillouin scattering has emerged as a unique elastography technique because of its merit of non-contact, label-free, and high-resolution mechanical imaging of biological cell and tissue.
Chenjun Shi, Hongyuan Zhang, Jitao Zhang
doaj +2 more sources
Pulsed stimulated Brillouin microscopy [PDF]
Optics Express, 2023 Stimulated Brillouin scattering is an emerging technique for probing the mechanical properties of biological samples. However, the nonlinear process requires high optical intensities to generate sufficient signal-to-noise ratio (SNR). Here, we show that the SNR of stimulated Brillouin scattering can exceed that of spontaneous Brillouin scattering with ...
Desmond M. Chow, Seok-Hyun Yun
openaire +3 more sources
In vivo assessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy [PDF]
Open Biology, 2022 In processes such as development and regeneration, where large cellular and tissue rearrangements occur, cell fate and behaviour are strongly influenced by tissue mechanics.
Camilo Riquelme-Guzmán +7 more
doaj +2 more sources
Heterodyne Brillouin microscopy for biomechanical imaging [PDF]
Biomedical Optics Express, 2021 Microscopic variations in material stiffness play a vital role in cellular scale biomechanics, but are difficult to measure in a natural 3D environment. Brillouin microscopy is a promising technology for such applications, providing non-contact label-free measurement of longitudinal modulus at microscopic resolution.
Michael A. Taylor +4 more
openaire +3 more sources
Mechanical mapping of mammalian follicle development using Brillouin microscopy [PDF]
Communications Biology, 2021 Chan et al. apply Brillouin microscopy to study changes in tissue material properties during mammalian follicle development. Focusing on the Brillouin loss tangent which is independent of the refractive index and mass density, they find that mammalian ...
Chii Jou Chan +2 more
doaj +2 more sources
Large evanescently-induced Brillouin scattering at the surrounding of a nanofibre
Nature Communications, 2022 The authors observe efficient Brillouin scattering generated by an evanescent field nearby a single pass sub-wavelength waveguide. This work creates an important bridge between Brillouin scattering in waveguides, Brillouin spectroscopy and microscopy.
Fan Yang +7 more
doaj +1 more source
Improving localization precision of Brillouin measurements using spectral autocorrelation analysis [PDF]
Journal of Innovative Optical Health Sciences, 2017 Brillouin spectroscopy is a powerful tool for measuring the mechanical properties of materials without contact. The sensitivity to mechanical changes that a Brillouin spectrometer can detect is determined by the precision to which a spectral peak can be ...
Eitan Edrei +2 more
doaj +1 more source
Nanophotonics, 2023 Brillouin–Raman combined confocal spectroscopy is a novel and powerful technique for providing non-contact and direct readout of the micro-regional chemical and mechanical properties of a material, and thus used in a broad range of applications ...
Su Yunhao +3 more
doaj +1 more source
Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS [PDF]
, 2018 Altered cellular biomechanics have been implicated as key photogenic triggers in age-related diseases. An aberrant liquid-to-solid phase transition, observed in in vitro reconstituted droplets of FUS protein, has been recently proposed as a possible ...
Antonacci, Giuseppe +3 more
core +3 more sources