Nature Reviews Methods PrimersThe field of Brillouin microscopy and imaging was established approximately 20 years ago, thanks to the development of non-scanning high-resolution optical spectrometers. Since then, the field has experienced rapid expansion, incorporating technologies from telecommunications, astrophotonics, multiplexed microscopy, quantum optics and machine learning.
Irina V Kabakova +2 more
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Pulsed stimulated Brillouin microscopy. [PDF]
Opt Express, 2023 Stimulated Brillouin scattering is an emerging technique for probing the mechanical properties of biological samples. However, the nonlinear process requires high optical intensities to generate sufficient signal-to-noise ratio (SNR). Here, we show that the SNR of stimulated Brillouin scattering can exceed that of spontaneous Brillouin scattering with ...
Chow DM, Yun SH.
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Progressive alteration of murine bladder elasticity in actinic cystitis detected by Brillouin microscopy [PDF]
Scientific ReportsBladder mechanical properties are critical for organ function and tissue homeostasis. Therefore, alterations of tissue mechanics are linked to disease onset and progression. This study aims to characterize the tissue elasticity of the murine bladder wall
Laura Martinez-Vidal +12 more
doaj +2 more sources
Motion-Tracking Brillouin Microscopy Evaluation of Normal, Keratoconic, and Post–Laser Vision Correction Corneas [PDF]
American Journal of Ophthalmology, 2023 Hongyuan Zhang +2 more
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Heterodyne Brillouin microscopy for biomechanical imaging. [PDF]
Biomed Opt Express, 2021 Microscopic variations in material stiffness play a vital role in cellular scale biomechanics, but are difficult to measure in a natural 3D environment. Brillouin microscopy is a promising technology for such applications, providing non-contact label-free measurement of longitudinal modulus at microscopic resolution.
Taylor MA +4 more
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Brillouin microscopy in cancer research: a review. [PDF]
J Biomed OptCancer is one of the leading diseases worldwide, continuing to pose a significant financial burden to national health systems and taking lives. These drive the development of early-stage cancer diagnostics, which is believed to be a crucial step in improving patients' life expectancy and long-term outcomes of cancer treatments.In this review, we ...
Falkner N +7 more
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Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin Microscopy [PDF]
Cancers, 2021 Vaibhav Mahajan +2 more
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Brillouin microscopy: assessing ocular tissue biomechanics. [PDF]
Curr Opin Ophthalmol, 2018 Assessment of corneal biomechanics has been an unmet clinical need in ophthalmology for many years. Many researchers and clinicians have identified corneal biomechanics as source of variability in refractive procedures and one of the main factors in keratoconus. However, it has been difficult to accurately characterize corneal biomechanics in patients.
Yun SH, Chernyak D.
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Large evanescently-induced Brillouin scattering at the surrounding of a nanofibre
Nature Communications, 2022 The authors observe efficient Brillouin scattering generated by an evanescent field nearby a single pass sub-wavelength waveguide. This work creates an important bridge between Brillouin scattering in waveguides, Brillouin spectroscopy and microscopy.
Fan Yang +7 more
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Subclinical Keratoconus Detection and Characterization Using Motion-Tracking Brillouin Microscopy [PDF]
OphthalmologyJ Bradley Randleman +2 more
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