Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. [PDF]
, 2010 Glaucoma is a collection of diseases characterized by multifactorial progressive changes leading to visual field loss and optic neuropathy most frequently due to elevated intraocular pressure (IOP).
Bell, Nicholas P +2 more
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Neuroprotective properties of Brimonidine
Офтальмохирургия, 2019 Purpose. To summarize relevant data from publications appearing in the peer-reviewed scientific literature since1991 about mechanisms of neurodegeneration in glaucoma and the possibilities of neuroprotection; in particular, analysis of the results of ...
Т. N. Mikhailova
doaj +1 more source
Risk Factors for Optic Disc Hemorrhage in the Low-Pressure Glaucoma Treatment Study [PDF]
, 2014 PurposeTo investigate risk factors for disc hemorrhage detection in the Low-Pressure Glaucoma Treatment Study.DesignCohort of a randomized, double-masked, multicenter clinical trial.MethodsLow-Pressure Glaucoma Treatment Study patients with at least 16 ...
De Moraes, Carlos Gustavo +7 more
core +1 more source
Controlling the Adsorption and Release of Ocular Drugs in Metal–Organic Frameworks: Effect of Polar Functional Groups [PDF]
, 2022 A series of UiO-66 materials with different functional groups (−H, −NH2, and −NO2) have been evaluated for the adsorption and release of a common ocular drug such as brimonidine tartrate.
Farrando Pérez, Judit +6 more
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A Topical Formulation of Melatoninergic Compounds Exerts Strong Hypotensive and Neuroprotective Effects in a Rat Model of Hypertensive Glaucoma [PDF]
, 2020 Melatonin is of great importance for regulating several eye processes, including pressure homeostasis. Melatonin in combination with agomelatine has been recently reported to reduce intraocular pressure (IOP) with higher efficacy than each compound alone.
Amato, Rosario +6 more
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Ocular metabolism and distribution of drugs in the rabbit eye : Quantitative assessment after intracameral and intravitreal administrations [PDF]
, 2022 Quantitation of ocular drug metabolism is important, but only sparse data is currently available. Herein, the pharmacokinetics of four drugs, substrates of metabolizing enzymes, was investigated in albino rabbit eyes after intracameral and intravitreal ...
del Amo, Eva M. +11 more
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Nummular keratitis: A rare manifestation of brimonidine allergy
Oman Journal of OphthalmologyA 32-year-old male, with juvenile open-angle glaucoma on chronic antiglaucoma therapy and recently introduced brimonidine eye drops to the treatment regimen, developed bilateral follicular conjunctivitis with subepithelial infiltrates (SEIs) initially ...
Maitha Al Asmi, Aisha Al Busaidi
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Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
BMC Ophthalmology, 2023 Background We report a case of uveal effusion in a nanophthalmic eye after topical use of brimonidine. Case presentation A 42-year-old male patient with nanophthalmos experienced sudden blurred vision in the right eye after using topical brimonidine when
Yakun Li, Qi Zhou
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Effect of brimonidine on central corneal thickness in normal tension glaucoma patients [PDF]
, 2019 Background: Brimonidine is a potent ocular hypotensive agent widely used in glaucoma treatment. A reduction in central corneal thickness can lead to an underestimation of intraocular pressure by Goldmann applanation tonometry and vice versa.
K., Praveena K. +2 more
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Indian Journal of Ophthalmology, 2014 Aims: The aim was to compare efficacy and cost-effectiveness of bimatoprost 0.03% and brimonidine 0.2% in primary open-angle glaucoma (POAG)/ocular hypertension (OHT). Settings and Design: Open, randomized, cross-over, comparative study.
Navreet Kaur Natt +3 more
doaj +1 more source