Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery [PDF]
, 2018 A cationic bis‐imidazolium‐based amphiphile was used to form thermoreversible nanostructured supramolecular hydrogels incorporating neutral and cationic drugs for the topical treatment of rosacea.
Amabilino, David B. +6 more
core +1 more source
Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. [PDF]
, 2010 Glaucoma is a collection of diseases characterized by multifactorial progressive changes leading to visual field loss and optic neuropathy most frequently due to elevated intraocular pressure (IOP).
Bell, Nicholas P +2 more
core +3 more sources
Augmented in vitro and in vivo Profiles of Brimonidine Tartrate Using Gelatinized-Core Liposomes
International Journal of Nanomedicine, 2022 Background The low entrapment efficiency of the hydrophilic drugs such as brimonidine tartrate (BRT) in liposomes represents a challenge that requires interventions.
Engy A Abdel Azim +4 more
semanticscholar +1 more source
24-h Efficacy of Glaucoma Treatment Options [PDF]
, 2016 Current management of glaucoma entails the medical, laser, or surgical reduction of intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate with either stability or delayed progression of visual loss.
Banu, Bozkurt. +8 more
core +2 more sources
Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children
Journal of Ophthalmology, 2021 Purpose. To investigate the effects of topical brimonidine 0.15% instillation on conjunctival injection after strabismus surgery in children. Methods.
Dong Hyun Kim +3 more
doaj +1 more source
The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review [PDF]
, 2017 The acute and chronic effects of repeated intravitreal antivascular endothelial growth factor (VEGF) injections on intraocular pressure have not been fully characterized, and the development of sustained ocular hypertension could adversely affect ...
Bracha, Peter +4 more
core +1 more source
Cardiovascular effects of timolol maleate, brimonidine or brimonidine/timolol maleate in concomitant therapy [PDF]
Acta Ophthalmologica Scandinavica, 2002 ABSTRACT.Purpose: To examine the influence on maximal exercise performance in young healthy volunteers of timolol 0.5%, brimonidine 0.2% or placebo versus brimonidine 0.2% and timolol 0.5% used concomitantly.Methods: The subjects in this prospective, double‐masked, crossover comparison were dosed 15 min prior to treadmill testing.
Jeanette A. Stewart +2 more
openaire +3 more sources
Changes in visual function after intraocular pressure reduction using antiglaucoma medications [PDF]
, 2009 Purpose To evaluate the change in visual function after starting glaucoma treatment and correlate this to a decrease in intraocular pressure (IOP) in primary open-angle glaucoma patients.Methods A prospective, randomized clinical trial was carried out ...
A Harris +22 more
core +2 more sources
Brimonidine 0.2% versus Brimonidine Purite 0.15% in Asian Ocular Hypertension
Journal of Ocular Pharmacology and Therapeutics, 2007 The aim of this study was to evaluate the efficacy and safety of brimonidine 0.2% versus brimonidine Purite 0.15% in Asians with ocular hypertension.This study was a prospective, randomized, observer-masked, short-term crossover trial. Eighty-six (86) Asian subjects with newly diagnosed ocular hypertension were randomly assigned to receive either ...
Chan Yun Kim, Gong Je Seong, Samin Hong
openaire +4 more sources
Evaluation of brimonidine-timolol fixed combination in patients of primary open-angle glaucoma
Indian Journal of Ophthalmology, 2013 The aim of present study was to compare the efficacy and safety of fixed combination of brimonidine and timolol with individual components used as monotherapy in patients of primary open angle glaucoma.
Sachin R Joshi +5 more
doaj +1 more source