Results 41 to 50 of about 8,852 (197)

Prevalence and clinical characteristics of Charles Bonnet syndrome in Madrid, Spain [PDF]

, 2014
Purpose: Charles Bonnet syndrome (CBS) is a condition characterized by development of visual hallucinations in patients with no cognitive impairment and significant loss of vision mainly caused by age-related macular degeneration (AMD) or glaucoma ...
García Feijoo, Julián, García Sánchez, Julián, Martínez de la Casa, Jose Maria, Porta-Etessam, Jesús, Saenz Frances, Federico, Santos Bueso, Enrique, Serrador García, Mercedes   +6 more
core   +2 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

A pharmacoeconomic analysis to determine the relative cost-effectiveness of bimatoprost 0.03% eye drops and brimonidine 0.2% eye drops in patients of primary open-angle glaucoma/ocular hypertension

Indian Journal of Ophthalmology, 2014
Aims: The aim was to compare efficacy and cost-effectiveness of bimatoprost 0.03% and brimonidine 0.2% in primary open-angle glaucoma (POAG)/ocular hypertension (OHT). Settings and Design: Open, randomized, cross-over, comparative study.
Navreet Kaur Natt, A Gupta, G Singh, T Singh   +3 more
doaj   +1 more source

Comparisons of efficacy and safety between preserved and preservative-free brimonidine tartrate in glaucoma and ocular hypertension: a parallel-grouped, randomized trial

Scientific Reports, 2023
This multicenter (four institutions), randomized, investigator-masked, parallel-group clinical trial evaluated and compared the efficacy and safety of preservative-free and preserved brimonidine tartrate 0.15% in open-angle glaucoma and ocular ...
Ko Eun Kim, Chang Kyu Lee, Jonghoon Shin, Yuri Kim, Seungsoo Rho   +4 more
doaj   +1 more source

Brimonidine-Soluplus Nanomicelles: Preparation and in-vitro evaluation

Iraqi Journal of Pharmaceutical Sciences
Brimonidine is an active pharmaceutical ingredient used to treat glaucoma as a topical eye drop. Ophthalmic topical preparations are associated with low ocular bioavailability due to several physiological and analytical barriers.
Noor Al wiswasi, Fatima J. Al-Gawahri
doaj   +1 more source

Respiratuvar depression after accidental nasal ingestion of brimonidine eye drops in infant

Turkish Journal of Emergency Medicine, 2016
Objectives: Brimonidine tartrate is an alpha-2 agonist used for glaucoma treatment. It can lead to serious poisoning symptoms when misused by children.
Ali Gunes, Hasan Balik, Servet Yel, Halil Kocamaz, Mehmet Bosnak   +4 more
doaj   +1 more source

Patient Factors Influencing Intraocular Penetration of Brimonidine-Related Eye Drops in Adults: A Post Hoc Pooled Analysis

Ophthalmology and Therapy, 2023
Introduction The factors related to the ocular penetration of drugs after the administration of eye drops in humans have not been examined in detail. Therefore, this study assessed the influence of patient factors on the intraocular penetration of eye ...
Eriko Kunikane, Yusuke Orii, Akiko Inoue, Masaru Inatani   +3 more
doaj   +1 more source

Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. [PDF]

, 2019
There is a limit beyond which increasing either the concentration of a prostaglandin analog (PGA) or its dosing frequency fails to produce increases in ocular hypotensive efficacy with topical dosing.
Alm, Blondeau, Brubaker, Celebi, Chen, Cymbor, Eveleth, Foroozan, Friberg, Funk, Funk, Katz, Krieglstein, Lee, Lee, Lee, Lewis, Lindén, Lovering, McDougal, Nagasubramanian, Ogundele, Phelps, Prum, Seal, Selbach, Selbach, Sherwood, Sit, Sit, Strohmaier, Tsai, Walløe, Watts, Wilke, Zamora, Zamora   +36 more
core   +2 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model.

PLoS ONE
Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells (RGC). Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective properties. This study aimed to compare the neuroprotective effects of
Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene   +3 more
doaj   +1 more source