Results 31 to 40 of about 4,322 (154)

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Impact of mono‐ or multitherapy on ocular surface health and quality of life after 5 years of follow‐up in the Glaucoma Intensive Treatment Study (GITS)

Acta Ophthalmologica, Volume 104, Issue 5, Page 535-543, August 2026.
Abstract Aim To evaluate the impact of initial mono‐ versus multitherapy on the ocular surface and related quality of life after 5 years follow‐up in the Glaucoma Intensive Treatment Study (GITS). Method The study included patients with primary open‐angle glaucoma and pseudoexfoliation glaucoma who completed 5‐year follow‐up in GITS.
Gauti Jóhannesson, Christina Lindén, Johan Aspberg, Sabina Andersson‐Geimer, Anders Heijl, Boel Bengtsson, Dorothea Peters   +6 more
wiley   +1 more source

A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model.

PLoS ONE
Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells (RGC). Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective properties. This study aimed to compare the neuroprotective effects of
Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene   +3 more
doaj   +1 more source

Novel Uses of Brimonidine

Delhi Journal of Ophthalmology
Brimonidine tartrate is a third-generation, highly selective alpha 2 agonist currently available in various formulations and doses to treat ophthalmological conditions. The aim of this article was to review pharmacokinetics, mechanisms, side effects, and
Hikkalagutti. S. Kruthika, Chauhan Tulika, Patyal Sagarika, Bhardwaj Kanika, Dabas Garvita   +4 more
doaj   +1 more source

Comparative Analysis of Pupil Diameters in Light and Dark Conditions After Instillation of 0.15% Brimonidine Drops in Eyes With and Without Pseudoexfoliation Syndrome

Beyoglu Eye Journal, 2020
INTRODUCTION[|] This study aimed to compare pupil diameters in light and dark conditions after instillation of 0.15% brimonidine drops in eyes with and without pseudoexfoliation syndrome (PES).[¤]METHODS[|]Forty eyes of 40 patients in whom 0.15 ...
Sercan Cate, Çağlar Bektaş, Burak Turgut   +2 more
doaj   +1 more source

National Delphi consensus on laser and energy‐based treatments for rosacea

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1070-1076, August 2026.
Summary Background Various treatments are available for rosacea, including lasers and energy‐based devices (EBDs). However, the specific role of lasers and EBDs in rosacea management remains insufficiently defined in Germany. The aim of the study was to develop a comprehensive expert consensus on the use of lasers and EBDs in the treatment of rosacea ...
Lynhda Nguyen, Nikolaus Seeber, Uwe Paasch, Martin Schaller, Claudia Borelli, Syrus Karsai, Gerd Kautz, Tanja C. Fischer, Michael Drosner, Stefan Hammes, Konstantin Feise, Christian Raulin, Martina Kerscher, Gerd Gauglitz, Jens M. Baron, Stefan W. Schneider, Katharina Herberger   +16 more
wiley   +1 more source

Respiratuvar depression after accidental nasal ingestion of brimonidine eye drops in infant

Turkish Journal of Emergency Medicine, 2016
Objectives: Brimonidine tartrate is an alpha-2 agonist used for glaucoma treatment. It can lead to serious poisoning symptoms when misused by children.
Ali Gunes, Hasan Balik, Servet Yel, Halil Kocamaz, Mehmet Bosnak   +4 more
doaj   +1 more source

Nationaler Delphi‐Konsens zu Laser‐ und Energie‐basierten Behandlungen der Rosazea

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1070-1076, August 2026.
Zusammenfassung Hintergrund Für die Rosazea‐Behandlung steht ein breites Spektrum an Therapieoptionen zur Verfügung, darunter auch Laser‐ und Energie‐basierte Systeme (energy‐based devices, EBDs). Die konkrete Rolle dieser Verfahren für die Rosazea ist in Deutschland bislang jedoch nur unzureichend definiert.
Lynhda Nguyen, Nikolaus Seeber, Uwe Paasch, Martin Schaller, Claudia Borelli, Syrus Karsai, Gerd Kautz, Tanja C. Fischer, Michael Drosner, Stefan Hammes, Konstantin Feise, Christian Raulin, Martina Kerscher, Gerd Gauglitz, Jens M. Baron, Stefan W. Schneider, Katharina Herberger   +16 more
wiley   +1 more source

Long Term Glaucoma Drug Delivery Using a Topically Retained Gel/Microsphere Eye Drop

Scientific Reports, 2017
The purpose of this study was to characterize and determine the efficacy of a long-term, non-invasive gel/microsphere (GMS) eye drop for glaucoma. This novel drug delivery system is comprised of a thermoresponsive hydrogel carrier and drug-loaded polymer
Morgan V. Fedorchak, Ian P. Conner, Joel S. Schuman, Anthony Cugini, Steven R. Little   +4 more
doaj   +1 more source

Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Argon laser trabeculoplasty (ALT) is an intraocular pressure lowering method that is overall safe and powerful, but often complicated by transient postoperative intraocular pressure rises.
Božić Marija, Hentova-Senćanić Paraskeva, Kontić Đorđe, Marković Vujica, Marjanović Ivan   +4 more
doaj   +1 more source