Results 41 to 50 of about 5,631 (161)

Respiratuvar depression after accidental nasal ingestion of brimonidine eye drops in infant

open access: yesTurkish Journal of Emergency Medicine, 2016
Objectives: Brimonidine tartrate is an alpha-2 agonist used for glaucoma treatment. It can lead to serious poisoning symptoms when misused by children.
Ali Gunes   +4 more
doaj   +1 more source

Association of Nasal and Inhalant Corticosteroids With Pediatric Perioral Dermatitis: A TriNetX Retrospective Cohort Study

open access: yesPediatric Dermatology, Volume 43, Issue 5, Page 1158-1162, September/October 2026.
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle   +4 more
wiley   +1 more source

Clinical Characterization of Glaucoma in 63 Pet Rabbits (Oryctolagus cuniculus) in Japan

open access: yesVeterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To characterize the signalment and clinical presentation of glaucoma in pet rabbits. Animal Studied Client‐owned pet rabbits (n = 222) referred to an exotic specialty animal hospital for ophthalmic examination between 2007 and 2023.
Kumiko Kato   +3 more
wiley   +1 more source

A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model.

open access: yesPLoS ONE
Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells (RGC). Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective properties. This study aimed to compare the neuroprotective effects of
Ruta Maciulaitiene   +3 more
doaj   +1 more source

Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

open access: yesOphthalmology and Therapy, 2019
Introduction Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues ...
Keisuke Shinno   +5 more
doaj   +1 more source

From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications

open access: yesAdvanced Electronic Materials, Volume 12, Issue 16, 24 August 2026.
This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra   +2 more
wiley   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

open access: yesSmall, Volume 22, Issue 46, 18 August 2026.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem   +12 more
wiley   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

open access: yesSmall Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu   +3 more
wiley   +1 more source

Topical Brimonidine Delays Ultraviolet Radiation‐Induced Squamous Cell Carcinoma in Hairless Mice

open access: yes, 2022
We investigated whether topical brimonidine delayed or enhanced the development of squamous cell carcinoma (SCC) when ultraviolet radiation (UVR) was applied to a well-established murine model.
Fernanda E. Pinto   +9 more
core   +1 more source

Novel Uses of Brimonidine

open access: yesDelhi Journal of Ophthalmology
Brimonidine tartrate is a third-generation, highly selective alpha 2 agonist currently available in various formulations and doses to treat ophthalmological conditions. The aim of this article was to review pharmacokinetics, mechanisms, side effects, and
Hikkalagutti. S. Kruthika   +4 more
doaj   +1 more source

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