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Corneal Opacity Induced by Antiglaucoma Agents Other Than Brimonidine Tartrate
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Side-Effect Profile of Brimonidine Tartrate in Children
Ophthalmology, 2005To investigate brimonidine-related side effects and the efficacy of brimonidine in lowering intraocular pressure (IOP) in children with primary infantile and secondary glaucoma.Single-center, prospective, interventional, noncomparative case series.Eighty-three children (mean age, 7.84 years) met the inclusion criteria.Medical records were reviewed to ...
Sami, Al-Shahwan +5 more
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Pupillometry Study of Brimonidine Tartrate 0.2% and Apraclonidine 0.5%
The Journal of Clinical Pharmacology, 2011This study investigated possible effects of brimonidine tartrate 0.2% and apraclonidine 0.5% on pupil diameter. Ten subjects between 20 and 40 years of age participated. A Colvard pupillometer (Oasis Medical) was used to measure pupil diameter. Baseline and serial measurements were obtained at 3 luminance levels (>6.4,
Eulogio, Besada +4 more
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Brimonidine tartrate for the treatment of glaucoma
Expert Opinion on Pharmacotherapy, 2018Brimonidine tartrate is a commonly used eyedrop for short- and long-term lowering of intraocular pressure. Its use has been popularized due to its effects on aqueous suppression and uveoscleral outflow, as well as the suggestion of neuroprotection. Although available with alternative preservative vehicles, brimonidine is associated with high rates of ...
Daniel J, Oh +3 more
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Advances in Glaucoma Therapy: Brimonidine Tartrate
Seminars in Ophthalmology, 1997Brimonidine, a newly approved α2-adrenoceptor agonist, is a 2-imidazoline derivative which is more highly selective for the α2-adrenoceptor than either clonidine or apraclonidine. The mechanism of action by which it lowers intraocular pressure (IOP) involves a decrease in aqueous humor production and an increase in aqueous humor outflow through the ...
David S. Greenfield +2 more
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Vitreous concentration of topically applied brimonidine tartrate 0.2%
Ophthalmology, 2001To determine the vitreous concentration of brimonidine after topical administration of Alphagan.Prospective observational case series.Eighteen patients scheduled for elective pars plana vitrectomy.Brimonidine tartrate, 0.2%, was topically administered twice or three times daily for 4 to 14 days preoperatively in 13 patients.
A R, Kent +5 more
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Effect of Brimonidine Tartrate on Ocular Hemodynamics in Healthy Volunteers
Journal of Ocular Pharmacology and Therapeutics, 2001While alpha2-adrenergic agonists, such as brimonidine tartrate, significantly reduce the intraocular pressure (IOP), the presence of vasoconstrictor postsynaptic alpha2 receptors on vascular smooth muscle raise the possibility that brimonidine could potentially compromise ocular blood flow.
Jonescu-Cuypers, Christian Paul +7 more
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Effect of Brimonidine Tartrate 0.15% on Scotopic Pupil: Controlled Trial
Journal of Ocular Pharmacology and Therapeutics, 2007The aim of this study was to evaluate the duration of the effect of one single dose of brimonidine tartrate 0.15% on pupil diameter, under scotopic conditions, when applied topically in 1 eye of normal subjects.The eyes of 19 normal volunteers were randomized so that 1 eye had 1 drop of brimonidine tartrate 0.15% and the other received no medication ...
Gerente, Vanessa M. +4 more
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