Results 1 to 10 of about 7,031 (227)
Synthesis of Functionalized 3H-pyrrolo-[1,2,3-de] Quinoxalines via Gold-Catalyzed Intramolecular Hydroamination of Alkynes [PDF]
Molecules, 2023 A gold-catalyzed protocol to obtain functionalized 3H-pyrrolo [1,2,3-de] quinoxalines from suitable substituted N-alkynyl indoles has been proposed. The mild reaction conditions were revealed to be compatible with different functional groups, including ...
Antonia Iazzetti +5 more
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Protocol for stereodivergent asymmetric hydrogenation of quinoxalines [PDF]
STAR Protocols, 2023 Summary: Chiral 1,2,3,4-tetrahydroquinoxalines are ubiquitous in natural products and bioactive molecules. Herein, we disclose a protocol for stereodivergent asymmetric hydrogenation of disubstituted quinoxalines for the preparation of both cis- and ...
Mingyang Wang, Chenguang Liu, Qiang Liu
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Synthesis and Antimicrobial Activity of Some New Substituted Quinoxalines
Molecules, 2019 A number of new symmetrically and asymmetrically 2,3-disubstituted quinoxalines were synthesized through functionalization of 2,3-dichloroquinoxaline (2,3-DCQ) with a variety of sulfur and/or nitrogen nucleophiles.
Mohamed A. El-Atawy +3 more
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Benzylic C–H Oxidation: Recent Advances and Applications in Heterocyclic Synthesis [PDF]
MoleculesBenzylic C–H oxidation to form carbonyl compounds, such as ketones, is a fundamental transformation in organic synthesis as it allows for the preparation of versatile intermediates.
Nonhlelo Majola, Vineet Jeena
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Molecules, 2010 A microwave-induced iodine-catalyzed simple, rapid and convenient synthesis of different types of quinoxalines via condensation of 1,2-diamines with 1,2-dicarbonyl compounds has been accomplished with an excellent yield.
Debasish Bandyopadhyay +3 more
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Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules [PDF]
Acta Cirúrgica BrasileiraPurpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents.
Jannyely Moreira Neri +9 more
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Chemistry, 2021 Of the utmost importance of chirality in organic compounds and drugs, the present work reports structure-chirality relationship of three steroidal quinoxalines, which were synthesised by condensing diaminobenzenes with cholestenone.
Rashid Mehmood +4 more
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A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines
SynOpen, 2021 A highly efficient and catalyst-free protocol is reported for the synthesis of quinoxalines via the classical cyclocondensation reaction between aryldiamines and dicarbonyl compounds.
Vijayaragavan Elumalai, Jørn H. Hansen
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National Science Open, 2023 : Synthetic N-heterocyclic compounds, such as quinoxalines, have shown a crucial role in pharmaceutical as well as food and dye industries. However, the traditional synthesis toward N-heterocycles relies on multistep energy and cost-intensive non ...
Yu Feng +6 more
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Journal of Chemistry, 2021 4,5-Dihydropyrrolo [1,2-a]quinoxalines are interesting druggable scaffolds, with multifaceted biological properties, including anticancer properties targeting the G protein-coupled estrogen receptor 1 (GPER).
Gabriele Carullo +3 more
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