Results 31 to 40 of about 7,031 (227)

Fused-Ring Derivatives of Quinoxalines: Spectroscopic Characterization and Photoinduced Processes Investigated by EPR Spin Trapping Technique

Molecules, 2014
10-Ethyl-7-oxo-7,10-dihydropyrido[2,3-f]quinoxaline derivatives, synthesized as promising biologically/photobiologically active compounds were characterized by UV/vis, FT-IR and fluorescent spectroscopy.
Zuzana Barbieriková, Dana Dvoranová, Maroš Bella, Viktor Milata, Adriana Czímerová, Vlasta Brezová   +5 more
doaj   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, EarlyView.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]

, 2017
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang, Gu, Yucheng, Lu, Changhui, Shen, Qilong, Wu, Jiang   +4 more
core   +1 more source

A Negatively Curved Pyrene‐Fused Azaacene

Angewandte Chemie, EarlyView.
A pyrene‐fused azaacene derivative is reported in which steric overcrowding caused by eight phenyl substituents induces bending of the aromatic framework rather than twisting. ABSTRACT Non‐planar aromatic hydrocarbons display distorted π‐frameworks that give rise to unique optoelectronic properties.
Marco Carini, Miguel Martín‐Arroyo, Manuel Melle‐Franco, Aurelio Mateo‐Alonso   +3 more
wiley   +2 more sources

Radical Fluoroalkylation Reactions [PDF]

, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian, Cooke, María Victoria, Postigo, A.   +2 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some New Quinoxaline Derivatives

Pharmaceuticals, 2010
2-Chloro-3-methylquinoxaline was selected as a nucleus around which various molecular transformations were performed to obtain new compounds expected to possess optimized antimicrobial activity.
Ram Gopal Singhal, Syed Riaz Hashim, Sanjay Kumar Deivedi, Dharmchand Prasad Singh   +3 more
doaj   +1 more source

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy

Molecules, 2019
We report the synthesis and relevant pharmacological properties of the quinoxalinetacrine (QT) hybrid QT78 in a project targeted to identify new non-hepatotoxic tacrine derivatives for Alzheimer’s disease therapy.
Eva Ramos, Alejandra Palomino-Antolín, Manuela Bartolini, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, Abdelouahid Samadi, Carol V. Cortina, Mourad Chioua, Javier Egea, Alejandro Romero, José Marco-Contelles   +11 more
doaj   +1 more source

Preparation, structures and preliminary host–guest studies of fluorinated syn-bis-quinoxaline molecular tweezers

Beilstein Journal of Organic Chemistry, 2010
A series of polycyclic frameworks with fluorinated syn-facial quinoxaline sidewalls has been prepared as potential molecular tweezers for electron-rich guest compounds.
Markus Etzkorn, Jacob C. Timmerman, Matthew D. Brooker, Xin Yu, Michael Gerken   +4 more
doaj   +1 more source

Novel Synthetic Routes to Prepare Biologically Active Quinoxalines and Their Derivatives: A Synthetic Review for the Last Two Decades

Molecules, 2021
Quinoxalines, a class of N-heterocyclic compounds, are important biological agents, and a significant amount of research activity has been directed towards this class.
Hena Khatoon, Emilia Abdulmalek
doaj   +1 more source

A Combined Experimental and Theoretical Study of the Ammonium Bifluoride Catalyzed Regioselective Synthesis of Quinoxalines and Pyrido[2,3-b]pyrazines

, 2015
International audienceAmmonium bifluoride was efficiently used (at a 0.5 mol % loading) to catalyze the cyclocondensation between 1,2-arylenediamines and 1,2-dicarbonyl compounds at room temperature in methanol-water, affording quinoxalines and pyrido[2 ...
Chevallier, Floris, Domingo, Luis R, Dorcet, Vincent, Lassagne, Frédéric, Mongin, Florence, Roisnel, Thierry   +5 more
core   +3 more sources