Effects of brinzolamide on rabbit ocular blood flow in vivo and ex vivo [PDF]
International Journal of Ophthalmology, 2018 AIM: To investigate if significant improvement of optic disc blood flow (ODBF) occurs after instillation of brinzolamide onto rabbit eyes. METHODS: Testing of bilateral intraocular pressure (IOP) and left ODBF in 10 male rabbits took place every 3h over
Guofeng Yin +2 more
exaly +2 more sources
Frontiers in Pharmacology, 2019 Background: Brinzolamide as a carbonic anhydrase inhibitor could be combined with other intraocular pressure (IOP) lowering drugs for glaucoma and ocular hypertension (OHT), but the efficacy was controversial.
Yuanzhi Liu +5 more
exaly +3 more sources
Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension [PDF]
Clinical Ophthalmology, 2009 Henny JM Beckers, Jan SAG Schouten, Carroll AB WebersUniversity Eye Clinic, Maastricht, The NetherlandsAbstract: Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol
Henny JM Beckers +2 more
doaj +3 more sources
Effects of brinzolamide vs timolol as an adjunctive medication to latanoprost on circadian intraocular pressure control in primary open-angle glaucoma Japanese patients [PDF]
Clinical Ophthalmology, 2009 Makoto Ishikawa1,2, Takeshi Yoshitomi11Department of Ophthalmology, Akita University Faculty of Medicine, Akita, Japan; 2Department of Ophthalmology, Ogachi Central Hospital, Akita, JapanPurpose: To study the effect of the concomitant use of brinzolamide
Makoto Ishikawa, Takeshi Yoshitomi
doaj +3 more sources
24-hour intraocular pressure in glaucoma patients randomized to receive dorzolamide or brinzolamide in combination with latanoprost [PDF]
Clinical Ophthalmology, 2009 Yoshimi Nakamura, Shusaku Ishikawa, Yuko Nakamura, Hiroshi Sakai, Ichiko Henzan, Shoichi SawaguchiDepartment of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, JapanPurpose: To investigate the efficacy of dorzolamide 1% (bid or tid)
Yoshimi Nakamura +4 more
doaj +3 more sources
Brinzolamide-timolol suspension: acceptability and side effect profile [PDF]
Clinical Ophthalmology, 2011 This study aimed to determine the frequency, nature, and impact of side effects associated with the use of brinzolamide-timolol suspension, a topical ocular antihypertensive preparation.A questionnaire was distributed to 76 consecutive patients attending the Sunderland Eye Infirmary Glaucoma Service who were using the brinzolamide-timolol suspension ...
Doherty, MD, Fraser, SG, Phelan, PS
core +8 more sources
Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2016 In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R)-4-ethylamino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding interactions.
Huirong Zheng, Benyong Lou
doaj +3 more sources
Update and optimal use of a brinzolamide-timolol fixed combination in open-angle glaucoma and ocular hypertension [PDF]
Clinical Ophthalmology, 2011 Misha F Syed, Emma KR LoucksDepartment of Ophthalmology and Visual Sciences, The University of Texas Medical Branch, Galveston, TX, USAAbstract: Glaucoma encompasses a wide clinical spectrum of disease, with the common pathophysiology of progressive ...
Syed MF, Loucks EKR
doaj +4 more sources
A comparative study on the efficacy of brinzolamide/timolol versus brinzolamide/brimonidine fixed drug combinations in primary open-angle glaucoma [PDF]
Future Journal of Pharmaceutical Sciences, 2020 Background To compare the efficacy of brinzolamide 1%/timolol 0.5% fixed drug combination (BTFC) with brinzolamide 1%/brimonidine 0.2% fixed drug combination (BBFC) among the patients with primary open-angle glaucoma (POAG).
Sudeepthi Padala +6 more
doaj +3 more sources
Effects of 1% Topical Brinzolamide on Intraocular Pressure in Healthy Dogs [PDF]
Acta Scientiae Veterinariae, 2016 Background: Glaucoma is one of the most common causes of blindness in dogs, and is generally characterized by death of the retinal ganglion cells associated with a rapid loss of vision. Increased intraocular pressure (IOP) occurs in patients with primary
Dower, Nathalie Moro Bassil +7 more
core +5 more sources